ArticleThe Journal of cell biology1986
Control of erythroid differentiation: asynchronous expression of the anion transporter and the peripheral components of the membrane skeleton in AEV- and S13-transformed cells.
Article in The Journal of cell biology, 1986. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 51 citations in OpenAlex.
- The sorting of blood group active proteins during enucleation.ISBT science series · 2015Article
- Critical band 3 multiprotein complex interactions establish early during human erythropoiesis.Blood · 2011Article
- Analysis of the kinetics of band 3 diffusion in human erythroblasts during assembly of the erythrocyte membrane skeleton.British journal of haematology · 2010Article
- Resolving the distinct stages in erythroid differentiation based on dynamic changes in membrane protein expression during erythropoiesis.Proceedings of the National Academy of Sciences of the United States of America · 2009Article
- Relationships between DNA methylation and expression in erythrocyte membrane protein (band 3, protein 4.2, and beta-spectrin) genes during human erythroid development and differentiation.International journal of hematology · 2005Article
- Defective anion transport and marked spherocytosis with membrane instability caused by hereditary total deficiency of red cell band 3 in cattle due to a nonsense mutation.The Journal of clinical investigation · 1996Article
- Different sequences of expression of band 3, spectrin, and ankyrin during normal erythropoiesis and erythroleukemia.The American journal of pathology · 1993Article
- Unequal synthesis and differential degradation of alpha and beta spectrin during murine erythroid differentiation.The Journal of cell biology · 1988Article
- A fibronectin matrix is required for differentiation of murine erythroleukemia cells into reticulocytes.The Journal of cell biology · 1987Article
- Gelsolin is expressed in early erythroid progenitor cells and negatively regulated during erythropoiesis.The Journal of cell biology · 1987Article
- Erythroid anion transporter assembly is mediated by a developmentally regulated recruitment onto a preassembled membrane cytoskeleton.The Journal of cell biology · 1987Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
Chicken erythroblasts transformed with avian erythroblastosis virus or S13 virus provide suitable model systems with which to analyze the maturation of immature erythroblasts into erythrocytes. The transformed cells are blocked in differentiation at around the colony-forming unit-erythroid stage of development but can be induced to differentiate in vitro. Analysis of the expression and assembly of components of the membrane skeleton indicates that these cells simultaneously synthesize alpha-spectrin, beta-spectrin, ankyrin, and protein 4.1 at levels that are comparable to those of mature erythroblasts. However, they do not express any detectable amounts of anion transporter. The peripheral membrane skeleton components assemble transiently and are subsequently rapidly catabolized, resulting in 20-40-fold lower steady-state levels than are found in maturing erythrocytes. Upon spontaneous or chemically induced terminal differentiation of these cells expression of the anion transporter is initiated with a concommitant increase in the steady-state levels of the peripheral membrane-skeletal components. These results suggest that during erythropoiesis, expression of the peripheral components of the membrane skeleton is initiated earlier than that of the anion transporter. Furthermore, they point a key role for the anion transporter in conferring long-term stability to the assembled erythroid membrane skeleton during terminal differentiation.
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