ArticleThe Korean journal of internal medicine2019
Utility of shear wave elastography to detect papillary thyroid carcinoma in thyroid nodules: efficacy of the standard deviation elasticity.
Article in The Korean journal of internal medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.
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Who cites it
15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 25 citations in OpenAlex.
- SuperSonic shear imaging for the differentiation between benign and malignant thyroid nodules: a meta-analysis.Journal of endocrinological investigation · 2022Pooled it
- Shear wave elastography as a quantitative biomarker of diabetic peripheral neuropathy: A systematic review and meta-analysis.Frontiers in public health · 2022Pooled it
- Predictive value of real-time shear wave elastography combined with serum thyroglobulin in thyroid cancer.Cancer imaging : the official publication of the International Cancer Imaging Society · 2026Article
- Preliminary study on the influencing factors of Young's modulus of viscoelastic model detected by shear wave elasticity.Frontiers in medicine · 2025Article
- Combing superb microvascular imaging with shear wave elastography for risk stratification of Thyroid Imaging Reporting and Data System (TI-RADS) 4 thyroid nodules.Gland surgery · 2024Article
- Application of color doppler ultrasound and US shear wave elastography with connective tissue growth factor in the risk assessment of papillary thyroid carcinoma.BMC medical imaging · 2024Article
- Impact of Region-of-Interest Size on the Diagnostic Performance of Shear Wave Elastography in Differentiating Thyroid Nodules.Cancers · 2023Article
- Evaluation of ultrasound point shear wave elastography reliability in an elasticity phantom.Ultrasonography (Seoul, Korea) · 2022Article
- Evaluation of Ultrasound Elastography Combined With Chi-Square Automatic Interactive Detector in Reducing Unnecessary Fine-Needle Aspiration on TIRADS 4 Thyroid Nodules.Frontiers in oncology · 2022Article
- Diagnostic performance of C-TIRADS combined with SWE for the diagnosis of thyroid nodules.Frontiers in endocrinology · 2022Article
- Contrast-enhanced ultrasound and shear wave elastography in the diagnosis of ACR TI-RADS 4 and 5 category thyroid nodules coexisting with Hashimoto's thyroiditis.Frontiers in oncology · 2022Article
- Evaluation of thyroid nodules by shear wave elastography: a review of current knowledge.Journal of endocrinological investigation · 2021Review
- Assessment of perinodular stiffness in differentiating malignant from benign thyroid nodules.Endocrine connections · 2021Article
- Incremental diagnostic value of shear wave elastography combined with contrast-enhanced ultrasound in TI-RADS category 4a and 4b nodules.Journal of medical ultrasonics (2001) · 2020Article
- Re-Evaluation of 162 Malignant Thyroid Nodules that were Interpreted as Benign Based on Ultrasound Findings.Ultrasound international open · 2018Article
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
Abstract
BACKGROUND/
aimsThe aim of this study was to address the role of the elasticity index as a possible predictive marker for detecting papillary thyroid carcinoma (PTC) and quantitatively assess shear wave elastography (SWE) as a tool for differentiating PTC from benign thyroid nodules.
methodsOne hundred and nineteen patients with thyroid nodules undergoing SWE before ultrasound-guided fine needle aspiration and core needle biopsy were analyzed. The mean (EMean), minimum (EMin), maximum (EMax), and standard deviation (ESD) of SWE elasticity indices were measured.
resultsAmong 105 nodules, 14 were PTC and 91 were benign. The EMean, EMin, and EMax values were significantly higher in PTCs than benign nodules (EMean 37.4 in PTC vs. 23.7 in benign nodules, p = 0.005; EMin 27.9 vs. 17.8, p = 0.034; EMax 46.7 vs. 31.5, p < 0.001). The EMean, EMin, and EMax were significantly associated with PTC with diagnostic odds ratios varying from 6.74 to 9.91, high specificities (86.4%, 86.4%, and 88.1%, respectively), and positive likelihood ratios (4.21, 3.69, and 4.82, respectively). The ESD values were significantly higher in PTC than in benign nodules (6.3 vs. 2.6, p < 0.001). ESD had the highest specificity (96.6%) when applied with a cut-off value of 6.5 kPa. It had a positive likelihood ratio of 14.75 and a diagnostic odds ratio of 28.50.
conclusionThe shear elasticity index of ESD, with higher likelihood ratios for PTC, will probably identify nodules that have a high potential for malignancy. It may help to identify and select malignant nodules, while reducing unnecessary fine needle aspiration and core needle biopsies of benign nodules.
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