Evidence map›Paper›PMID 29466758›Full record

ArticleImmunity2018

T Cells in Nonlymphoid Tissues Give Rise to Lymph-Node-Resident Memory T Cells.

Lalit K Beura, Sathi Wijeyesinghe, Emily A Thompson, Marissa G Macchietto, Pamela C Rosato, Mark J Pierson, Jason M Schenkel, Jason S Mitchell, Vaiva Vezys, Brian T Fife and 2 more

Open access · bronzeAbstract read
In one paragraph

Article in Immunity, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 171 papers.

0numbers the graph read from it
0cells of the map it votes in
171citing papers in PubMed
13.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

171 citing papers in PubMed, 256 citations in OpenAlex.

  1. Article
  2. Article
  3. Immunogenomic landscape of the T cell repertoire after human lung transplantation and its clinical relevance.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2026
    Article
  4. PD-1 Inhibits CD4+ TRM-Mediated cDC1 Mobilization via Suppressing JAML in Human NSCLC.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Tissue-resident memory T cells reshapeFrontiers in immunology · 2026
    Review
  14. Article
  15. Article
  16. Review
  17. Discovery of intrahepatic CD103Experimental & molecular medicine · 2025
    Article
  18. Article
  19. Review
  20. Review

111 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Lalit K BeuraDepartment of Microbiology and Immunology, University of Minnesota, Minneapolis, MN 55455, USA; Center for Immunology, University of Minnesota, Minneapolis, MN 55455, USA.
Sathi WijeyesingheDepartment of Microbiology and Immunology, University of Minnesota, Minneapolis, MN 55455, USA; Center for Immunology, University of Minnesota, Minneapolis, MN 55455, USA.
Emily A ThompsonDepartment of Microbiology and Immunology, University of Minnesota, Minneapolis, MN 55455, USA; Center for Immunology, University of Minnesota, Minneapolis, MN 55455, USA.
Marissa G MacchiettoInstitute for Health Informatics, University of Minnesota, Minneapolis, MN, 55455, USA.
Pamela C RosatoDepartment of Microbiology and Immunology, University of Minnesota, Minneapolis, MN 55455, USA; Center for Immunology, University of Minnesota, Minneapolis, MN 55455, USA.
Mark J PiersonDepartment of Microbiology and Immunology, University of Minnesota, Minneapolis, MN 55455, USA; Center for Immunology, University of Minnesota, Minneapolis, MN 55455, USA.
Jason M SchenkelDepartment of Microbiology and Immunology, University of Minnesota, Minneapolis, MN 55455, USA; Center for Immunology, University of Minnesota, Minneapolis, MN 55455, USA.
Jason S MitchellCenter for Immunology, University of Minnesota, Minneapolis, MN 55455, USA; Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN 55455, USA.
Vaiva VezysDepartment of Microbiology and Immunology, University of Minnesota, Minneapolis, MN 55455, USA; Center for Immunology, University of Minnesota, Minneapolis, MN 55455, USA.
Brian T FifeCenter for Immunology, University of Minnesota, Minneapolis, MN 55455, USA; Department of Medicine, University of Minnesota, Minneapolis, MN 55455, USA.
Steven ShenInstitute for Health Informatics, University of Minnesota, Minneapolis, MN, 55455, USA.
David MasopustDepartment of Microbiology and Immunology, University of Minnesota, Minneapolis, MN 55455, USA; Center for Immunology, University of Minnesota, Minneapolis, MN 55455, USA. Electronic address: masopust@umn.edu.
University of Minnesota · USUniversity of Minnesota Medical Center · US

Funding

Mucosal T Cell Memory to PathogensR01AI084913 · NIAID · UNIVERSITY OF MINNESOTA · PI MASOPUST, DAVID · 2010 to 2023
$5.8M
IMMUNOLOGY TRAINING PROGRAMT32AI007313 · NIAID · UNIVERSITY OF MINNESOTA TWIN CITIES · PI Carla Rothlin · 1989 to 2026
$5.7M
Regulation of T cell immunity within the female reproductive tractR01AI111671 · NIAID · UNIVERSITY OF MINNESOTA · PI MASOPUST, DAVID · 2014 to 2018
$2.4M
Mucosal T cell memory to pathogensR37AI084913 · NIAID · UNIVERSITY OF MINNESOTA · PI DAVID MASOPUST · 2024 to 2026
$1.7M
Howard Hughes Medical InstituteNIAID NIH HHS R01 AI084913NIAID NIH HHS R01 AI111671NIAID NIH HHS R37 AI084913NIAID NIH HHS T32 AI007313
6 · The paper itself

Abstract

Immunosurveillance of secondary lymphoid organs (SLO) is performed by central memory T cells that recirculate through blood. Resident memory T (Trm) cells remain parked in nonlymphoid tissues and often stably express CD69. We recently identified Trm cells within SLO, but the origin and phenotype of these cells remains unclear. Using parabiosis of "dirty" mice, we found that CD69 expression is insufficient to infer stable residence of SLO Trm cells. Restimulation of nonlymphoid memory CD8

Indexed as

AnimalsAntigens, CDAntigens, Differentiation, T-LymphocyteCD69 AntigensCD8-Positive T-LymphocytesFemaleImmunologic MemoryLectins, C-TypeLymph NodesLymphocytic ChoriomeningitisMiceMice, Inbred C57BLAntigens, CDAntigens, Differentiation, T-LymphocyteCD69 AntigensLectins, C-Typelocal recall immunizationnon-lymphoid tissueregionalized immunosurveillanceresident memory T cellssecondary lymphoid organs

Identifiers

PMID29466758
PMCPMC5828517
OpenAlexW2788546163

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.