Evidence map›Paper›PMID 29466754›Full record

ReviewImmunity2018

Understanding Subset Diversity in T Cell Memory.

Stephen C Jameson, David Masopust

Abstract readReview
In one paragraph

Review in Immunity, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 359 papers.

0numbers the graph read from it
0cells of the map it votes in
359citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

359 citing papers in PubMed.

  1. Trial
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  5. Interferon regulatory factors orchestrate CD8International journal of molecular medicine · 2026
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Stage-dependent interaction between circulating and tissue-resident memory CD4Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2026
    Article
  12. ATR kinase inhibitors induce mitochondrial fission in CD8bioRxiv : the preprint server for biology · 2026
    Article
  13. Article
  14. CD8Nature reviews. Cardiology · 2026
    Review
  15. CD8Science China. Life sciences · 2026
    Review
  16. Article
  17. Review
  18. Article
  19. Article
  20. KLF2 overrides the resident memory CD8 T cell differentiation program, in opposition to KLF3.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article

299 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Stephen C JamesonCenter for Immunology, Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN 55414, USA. Electronic address: james024@umn.edu.
David MasopustDepartment of Microbiology and Immunology, University of Minnesota, Minneapolis, MN 55414, USA. Electronic address: masopust@umn.edu.

Funding

T Cell HomeostasisR01AI038903 · NIAID · UNIVERSITY OF MINNESOTA TWIN CITIES · PI STEPHEN C JAMESON · 2001 to 2026
$5.9M
Mucosal T Cell Memory to PathogensR01AI084913 · NIAID · UNIVERSITY OF MINNESOTA · PI MASOPUST, DAVID · 2010 to 2023
$5.8M
Regulation of T cell immunity within the female reproductive tractR01AI111671 · NIAID · UNIVERSITY OF MINNESOTA · PI MASOPUST, DAVID · 2014 to 2018
$2.4M
Mucosal T cell memory to pathogensR37AI084913 · NIAID · UNIVERSITY OF MINNESOTA · PI DAVID MASOPUST · 2024 to 2026
$1.7M
NIAID NIH HHS R01 AI038903NIAID NIH HHS R01 AI084913NIAID NIH HHS R01 AI111671NIAID NIH HHS R37 AI084913
6 · The paper itself

Abstract

Considerable advances have been made in recent years in understanding the generation and function of memory T cells. Memory T cells are typically parsed into discreet subsets based on phenotypic definitions that connote distinct roles in immunity. Here we consider new developments in the field and focus on how emerging differences between memory cells with respect to their trafficking, metabolism, epigenetic regulation, and longevity may fail to fit into small groups of "memory subsets." Rather, the properties of individual memory T cells fall on a continuum within each of these and other parameters. We discuss how this continuum influences the way that the efficacy of vaccination is assessed, as well as the suitability of a memory population for protective immunity.

Indexed as

AnimalsCell DifferentiationCell MovementEpigenomicsHumansImmunologic MemoryT-Lymphocyte Subsets

Identifiers

PMID29466754
PMCPMC5863745

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.