Evidence map›Paper›PMID 29466450›Full record

ArticlePloS one2018

Inclusion of live yeast and mannan-oligosaccharides in high grain-based diets for sheep: Ruminal parameters, inflammatory response and rumen morphology.

Tatiana Garcia Diaz, Antonio Ferriani Branco, Fernando Alberto Jacovaci, Clóves Cabreira Jobim, Dheyme Cristina Bolson, João Luiz Pratti Daniel

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
12.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 68 citations in OpenAlex.

  1. Thymol modulates rumen barrier function and inflammation in feed-restricted lambs.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2026
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Tatiana Garcia DiazDepartment of Animal Science, State University of Maringá; Av. Colombo, Bloco J45, Maringá, PR, Brazil.ORCID 0000-0003-1700-3382
Antonio Ferriani BrancoDepartment of Animal Science, State University of Maringá; Av. Colombo, Bloco J45, Maringá, PR, Brazil.
Fernando Alberto JacovaciDepartment of Animal Science, State University of Maringá; Av. Colombo, Bloco J45, Maringá, PR, Brazil.
Clóves Cabreira JobimDepartment of Animal Science, State University of Maringá; Av. Colombo, Bloco J45, Maringá, PR, Brazil.
Dheyme Cristina BolsonDepartment of Animal Science, State University of Maringá; Av. Colombo, Bloco J45, Maringá, PR, Brazil.
João Luiz Pratti DanielDepartment of Animal Science, State University of Maringá; Av. Colombo, Bloco J45, Maringá, PR, Brazil.
Universidade Estadual de Maringá · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The objective of this study was to evaluate the effects of dietary supplementation with live yeast (Saccharomyces cerevisiae), mannan-oligosaccharides and the combination of these additives on the inflammatory response, ruminal parameters and rumen morphology of sheep fed a high grain-based diet. Thirty-Two Dorper x Santa Ines crossbred lambs with an average weight of 24±2 kg were distributed in a completely randomized design. The animals were housed in individual stalls and fed ad libitum. Diet treatments were: Control (without additive); LY (2 g/kg DM of live yeast, Saccharomyces cerevisiae), MOS (2 g/kg DM of mannan-oligosaccharides) and LY+MOS (2 g/kg DM of LY + 2 g/kg DM of MOS). The experiment lasted 42 days. The supplementation with MOS alone and the additives combination resulted in increased ruminal pH (P<0.01), while the total concentrations of short chain fatty acids (SCFA) in the rumen were higher (P<0.05) only in the diets with LY and MOS. Ammonia (NH3) concentration in the rumen decreased (P<0.04) with the additives usage. Diets with LY, MOS and with additives combination reduced (P<0.01) the levels of lipopolysaccharides (LPS) in the plasma with values of 0.46; 0.44 and 0.04 EU/mL, respectively when compared to the control (0.93 EU/mL). MOS and LY+MOS treatments had reduced stratum corneum thickness (P<0.01) in comparison to the control treatment. The total thickness of ruminal epithelium was lower with the addition of MOS in the diet (P<0.03) than with LY additive. The incidence and severity of hepatic abscesses in animals whose diet was supplemented with LY and LY+MOS was lower (P<0.05) than in animals fed the control diet. The use of LY, MOS and LY+MOS in the high-concentrate diets for sheep reduced NH3 concentrations and LPS translocation into the bloodstream. Diets containing MOS and LY+MOS enhanced the health of the ruminal epithelium by reducing the thickness of the stratum corneum, and diets containing LY and LY+MOS decreased the incidence and severity of hepatic abscesses.

Indexed as

Animal FeedSaccharomyces cerevisiaeWhole GrainsAmmoniaAnimalsLipopolysaccharidesMannansOligosaccharidesRumenSheep, DomesticAmmoniaLipopolysaccharidesMannansOligosaccharides

Identifiers

PMID29466450
PMCPMC5821403
OpenAlexW2790479006

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.