Evidence map›Paper›PMID 29466097›Full record

ArticleTelemedicine journal and e-health : the official journal of the American Telemedicine Association2019

A Clinical Decision Support System for Diabetic Retinopathy Screening: Creating a Clinical Support Application.

Pedro Romero-Aroca, Aida Valls, Antonio Moreno, Ramon Sagarra-Alamo, Josep Basora-Gallisa, Emran Saleh, Marc Baget-Bernaldiz, Domenec Puig

Abstract read
In one paragraph

Article in Telemedicine journal and e-health : the official journal of the American Telemedicine Association, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Pedro Romero-Aroca1 Ophthalmology Service, Hospital Universitat Sant Joan, Institut de Investigacio Sanitaria Pere Virgili (IISPV), Universitat Rovira i Virgili, Reus, Spain.
Aida Valls2 Department of Computer Engineering and Mathematics, Universitat Rovira i Virgili, Reus, Spain.
Antonio Moreno2 Department of Computer Engineering and Mathematics, Universitat Rovira i Virgili, Reus, Spain.
Ramon Sagarra-Alamo3 Reus-Priorat Health Care Area, Institut Catala de la Salut (ICS), Institut de Investigació Sanitària Pere Virgili (IISPV), Universitat Rovira i Virgili, Reus, Spain.
Josep Basora-Gallisa3 Reus-Priorat Health Care Area, Institut Catala de la Salut (ICS), Institut de Investigació Sanitària Pere Virgili (IISPV), Universitat Rovira i Virgili, Reus, Spain.
Emran Saleh2 Department of Computer Engineering and Mathematics, Universitat Rovira i Virgili, Reus, Spain.
Marc Baget-Bernaldiz1 Ophthalmology Service, Hospital Universitat Sant Joan, Institut de Investigacio Sanitaria Pere Virgili (IISPV), Universitat Rovira i Virgili, Reus, Spain.
Domenec Puig2 Department of Computer Engineering and Mathematics, Universitat Rovira i Virgili, Reus, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe aim of this study was to build a clinical decision support system (CDSS) in diabetic retinopathy (DR), based on type 2 diabetes mellitus (DM) patients.

methodWe built a CDSS from a sample of 2,323 patients, divided into a training set of 1,212 patients, and a testing set of 1,111 patients. The CDSS is based on a fuzzy random forest, which is a set of fuzzy decision trees. A fuzzy decision tree is a hierarchical data structure that classifies a patient into several classes to some level, depending on the values that the patient presents in the attributes related to the DR risk factors. Each node of the tree is an attribute, and each branch of the node is related to a possible value of the attribute. The leaves of the tree link the patient to a particular class (DR, no DR).

resultsA CDSS was built with 200 trees in the forest and three variables at each node. Accuracy of the CDSS was 80.76%, sensitivity was 80.67%, and specificity was 85.96%. Applied variables were current age, gender, DM duration and treatment, arterial hypertension, body mass index, HbA1c, estimated glomerular filtration rate, and microalbuminuria. DISCUSSION: Some studies concluded that screening every 3 years was cost effective, but did not personalize risk factors. In this study, the random forest test using fuzzy rules permit us to build a personalized CDSS.

conclusionsWe have developed a CDSS that can help in screening diabetic retinopathy programs, despite our results more testing is essential.

Indexed as

Decision TreesAgedAged, 80 and overAge FactorsAge of OnsetBlood PressureBody Mass IndexDecision Support Systems, ClinicalDiabetic RetinopathyFemaleGlycated HemoglobinHumansKidney Function TestsMaleMass ScreeningMiddle AgedGlycated Hemoglobin

Identifiers

PMID29466097
PMCPMC6352499

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.