Evidence map›Paper›PMID 29466084›Full record

ArticleJournal of adolescent and young adult oncology2018

Fertility-Related Perceptions and Impact on Romantic Relationships Among Adult Survivors of Childhood Cancer.

Vicky Lehmann, Leena Nahata, Amanda C Ferrante, Jennifer A Hansen-Moore, Nicholas D Yeager, James L Klosky, Cynthia A Gerhardt

Open access · greenAbstract read
In one paragraph

Article in Journal of adolescent and young adult oncology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 2 pooled it
6.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 2 syntheses or guidelines pooled it, 39 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
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  7. Review
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  9. Article
  10. Article
  11. Fertility-related worry among emerging adult cancer survivors.Journal of assisted reproduction and genetics · 2022
    Article
  12. Article
  13. Review
  14. Article
  15. Facing the unknown: uncertain fertility in young adult survivors of childhood cancer.Journal of cancer survivorship : research and practice · 2021
    Article
  16. Article
  17. Pediatric oncofertility: an update.Translational andrology and urology · 2020
    Review
  18. Fertility-related services in pediatric oncology across the cancer continuum: a clinic overview.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2020
    Article
  19. 2019 Pediatric Initiative Network: Progress, Proceedings, and Plans.Journal of adolescent and young adult oncology · 2020
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Vicky Lehmann1 Center for Biobehavioral Health, The Research Institute at Nationwide Children's Hospital , Columbus, Ohio.
Leena Nahata1 Center for Biobehavioral Health, The Research Institute at Nationwide Children's Hospital , Columbus, Ohio.
Amanda C Ferrante1 Center for Biobehavioral Health, The Research Institute at Nationwide Children's Hospital , Columbus, Ohio.
Jennifer A Hansen-Moore3 Department of Pediatrics, The Ohio State University , Columbus, Ohio.
Nicholas D Yeager3 Department of Pediatrics, The Ohio State University , Columbus, Ohio.
James L Klosky2 Department of Psychology, St. Jude Children's Research Hospital , Memphis, Tennessee.
Cynthia A Gerhardt1 Center for Biobehavioral Health, The Research Institute at Nationwide Children's Hospital , Columbus, Ohio.
Nationwide Children's Hospital · USSt. Jude Children's Research Hospital · USThe Ohio State University · US

Funding

Translational Therapeutics Research Program (TT)P30CA016058 · NCI · OHIO STATE UNIVERSITY · PI Tasleem J Padamsee · 1985 to 2026
$132.3M
The Ohio State University Center for clinical and Translational ScienceUL1TR001070 · NCATS · OHIO STATE UNIVERSITY · PI JACKSON, REBECCA D · 2013 to 2017
$22.6M
NCATS NIH HHS UL1 TR001070NCI NIH HHS P30 CA016058
6 · The paper itself

Abstract

purposeTo present an overview of fertility-related perceptions and describe the perceived negative/positive impact of (potential) infertility on romantic relationships among childhood cancer survivors.

methodsMale and female long-term childhood cancer survivors (N = 92) aged 22-43 and 7-37 years postdiagnosis, completed an online survey about fertility-related perceptions (i.e., knowledge, beliefs, uncertainty, concern, and attitudes toward testing) and romantic relationships. Potential differences based on sociodemographic/cancer-specific factors were tested.

resultsMost survivors (82.4%, n = 75) knew about infertility risk due to childhood cancer treatment. Seventy percent (n = 65) reported being told they were personally at risk, but less than one-third believed it (29.2%, n = 19/65). Half of survivors (48.9%, n = 45) never underwent fertility testing and were unaware of their fertility status. Fertility-related uncertainty and concerns were more common among survivors without children and those who desired (additional) children (d's > 0.5). Among survivors without biological children (n = 52), partnered survivors felt more uncertain about their fertility than singles (d = 0.8). Ten survivors (10.9%) reported a negative impact of infertility on romantic relationships, 6 (6.5%) reported a positive impact, and 7 (7.6%) reported both (e.g., pressure on relationship, fights, break-ups, being closer, and open partner communication).

conclusionsFertility-related perceptions varied among survivors, but the majority never underwent fertility testing. Uncertainty or concerns differed by current circumstances (e.g., wanting children and relationship status). Providers should routinely discuss potential infertility and offer testing throughout survivorship. A negative impact on romantic relationships may seem small, but should be considered for survivors who desire children and may discover they are infertile in the future.

Indexed as

AdolescentAdultCancer SurvivorsChildEmotionsFemaleFertilityHumansMaleNeoplasmsPerceptionSexual PartnersYoung Adultadult childhood cancer survivorsfertility testingoncofertilityromantic relationshipssurvivorship care

Identifiers

PMID29466084
PMCPMC6083209
OpenAlexW2790296379

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.