ArticleSexually transmitted diseases2018
Reported Primary and Secondary Syphilis Cases in the United States: Implications for HIV Infection.
Article in Sexually transmitted diseases, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 44 citations in OpenAlex.
- Visual clues - dermatological manifestations of sexually transmitted infections in men.Nature reviews. Urology · 2026Review
- The Return of an Old Foe: Syphilis Among Women.Clinical obstetrics and gynecology · 2025Review
- Sexual behavior stigma and HIV/STI biospecimen self-collection among cisgender gay, bisexual, and other sexually minoritized men in the United States.BMC infectious diseases · 2024Article
- Pre-Exposure Prophylaxis Care Cascade Among Men Who Have Sex with Men Engaging in Partner Notification Services at a Sexually Transmitted Infections Clinic.AIDS research and human retroviruses · 2024Article
- A Potential Screening Strategy to Identify Probable Syphilis Infections in the Urban Emergency Department Setting.Open forum infectious diseases · 2024Article
- Granulomatous secondary syphilis with pulmonary involvement.JAAD case reports · 2024Article
- Oropharyngeal Secondary Syphilis Mimicking Metastatic Lymphoma in an HIV-Positive Patient.Cureus · 2023Article
- Lifetime prevalence of syphilis infection among predominantly Black sexual and gender minorities living with HIV in Atlanta, Georgia: a cross-sectional analysis.Ethnicity & health · 2023Article
- Sexually transmitted infection knowledge among men who have sex with men in Nairobi, Kenya.PloS one · 2023Article
- Tertiary syphilis mimicking metastatic rectal cancer.Journal of surgical case reports · 2022Article
- Intersection of Syphilis and Human Immunodeficiency Virus (HIV) Networks to Identify Opportunities to Enhance HIV Prevention.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2022Article
- Article
- Novel radiographic presentation of primary syphilis of the tonsil.Radiology case reports · 2021Article
- Bilateral Cranial Nerve VI Palsies in Cryptococcal Meningitis, HIV, and Syphilis: A Case Report.Clinical practice and cases in emergency medicine · 2021Article
- Two Potential Syphilis Vaccine Candidates Inhibit Dissemination ofFrontiers in immunology · 2021Article
- Ending the HIV Epidemic: Contributions Resulting From Syphilis Partner Services.Sexually transmitted diseases · 2020Article
- PrEP Nonadherence, White Coat Dosing, and HIV Risk Among a Cohort of MSM.Open forum infectious diseases · 2020Article
- Laboratory Diagnostic Tools for Syphilis: Current Status and Future Prospects.Frontiers in cellular and infection microbiology · 2020Review
- Unexplained bone pain and sexual addiction.BMJ case reports · 2018Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
backgroundRecent increases in syphilis among men who have sex with men (MSM) are especially concerning, given the biologic and epidemiologic associations between syphilis and HIV infection. We sought to better describe the current epidemiology of primary and secondary (P&S) syphilis and the prevalence of HIV infection among reported P&S syphilis cases by demographic group, including sex of sex partner, in the United States in 2016.
methodsWe reviewed national P&S syphilis case report data from 2016, including available risk factor information such as sex of sex partner and HIV status. Data were extracted from the National Electronic Telecommunications System for Surveillance, the system through which Centers for Disease Control and Prevention receives notifiable sexually transmitted disease data from all 50 states and the District of Columbia. The proportion of cases with HIV coinfection was calculated using cases with known HIV status as the denominator.
resultsOf 27,814 P&S syphilis cases reported in 2016, 58.1% were among MSM, 13.9% were among men who have sex with women only, 11.0% were among women, and 16.9% were among men without data on sex of sex partners. Similar patterns were observed across geographic regions, race/ethnicity groups, and most age groups. Overall, 38.5% of reported P&S syphilis cases with known HIV status were coinfected with HIV. The prevalence of HIV coinfection was highest among MSM (47.0%) compared with men who have sex with women only (10.7%) or women (4.1%). Among MSM with P&S syphilis, the prevalence of HIV coinfection was highest among black MSM, ranging from 33.8% among black MSM aged 15 to 19 years to 77.8% among black MSM aged 45 to 49 years.
conclusionsThese data underscore the epidemiologic linkages between syphilis and HIV, particularly among MSM. Primary and secondary syphilis may represent an opportunity to prevent HIV infection among persons who are HIV negative and identify and link to care persons living with HIV infection but not currently engaged in care.
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