Evidence map›Paper›PMID 29465549›Full record

Trial reportMedicine2018

Cardiorespiratory parameters and glycated hemoglobin of patients with type 2 diabetes after a rehabilitation program.

Natália da Silva Freitas Marques, Luiz Carlos de Abreu, Bárbara Vieira Dos Santos, Cândido Ferreira Rodrigues Neto, José Rener Cordeiro da Silva, Karine Ketlem de Souza Braga, Kariny da Silva Uchôa, Laila Maria Silva Moraes, Leillane Cristina de Paiva Ferreira, Natanael Guimaraes Ribeiro and 4 more

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06896630 (Effect of Long-Term Use of Tenofovir), which is not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06896630 not yet recruitingnot on this mapstarted 2025, after this paper: background citation

Effect of Long-Term Use of Tenofovir (TDF) on Renal Function in Patients With Chronic Hepatitis B

TypeobservationalSponsorAssiut UniversityRan2025 to 2026Enrolled172ConditionsTenofovir Disoproxil Fumarate, Renal Function Disorder, Chronic HBV InfectionArmsTenofovir Disoproxil Fumarate (TDF)
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 1 institution in 1 country.

Natália da Silva Freitas MarquesLaboratory of Study Design and Scientific Writing of the Faculty of Medicine of ABC, Prince of Wales, Santo André/SP-CEP, Brazil Research Laboratory of UNINORTE-Baron College of Rio Branco, Alameda Hungary, Rio Branco/AC-CEP, Brazil.
Luiz Carlos de Abreu
Bárbara Vieira Dos Santos
Cândido Ferreira Rodrigues Neto
José Rener Cordeiro da Silva
Karine Ketlem de Souza Braga
Kariny da Silva Uchôa
Laila Maria Silva Moraes
Leillane Cristina de Paiva Ferreira
Natanael Guimaraes Ribeiro
Savio Lima Dos Santos
Tayná Almeida da Silva
Paulo Evaristo de Andrade
Rodrigo Daminello Raimundo
Faculdade de Medicina do ABC · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionCardiovascular autonomic dysfunction reflex of the pathophysiology of diabetes mellitus (DM) favors an increase in morbidity and mortality related to cardiovascular events, and for this reason has been one of the most studied clinical entities.

methodAn experimental study of a randomized clinical trial type was therefore proposed to analyze the hemodynamic and glycemic response after the practice of a rehabilitation program in patients with type 2 diabetes mellitus (T2DM). In this clinical trial the patients will initially be submitted to an evaluation protocol that consists of assessing blood pressure, heart rate, Borg scale, respiratory rate, oxygen saturation, distance traveled through the 6-minute walk test, quality of life questionnaire, Pittsburgh sleep quality questionnaire, and still glycated hemoglobin and heart rate variability through the cardiofrequency meter. After careful evaluation of the patients, they will be submitted to a metabolic rehabilitation program composed of aerobic and resisted exercises, performed for 12 weeks, in 3 weekly meetings of 60 minutes each. With such evaluations, it will be possible to construct with evidence that it is possible to work safer metabolic rehabilitation programs in patients with T2DM or other diseases that generate cardiovascular risks, guaranteeing them an improvement in cardiorespiratory fitness, hemodynamic and glycemic variables, allowing improvement of the quality of life. ETHICS AND DISSEMINATION: The protocol is approved by the host institution's ethics committee under the number 1.616.721. Results will be disseminated via peer-reviewed journal articles and conferences. This clinical trial is registered at ClinicalTrials.gov identifier: NCT3094767.

Indexed as

Diabetes Mellitus, Type 2AdultBlood GlucoseBlood PressureClinical ProtocolsExerciseFemaleGlycated HemoglobinHeart RateHumansMaleOxygen ConsumptionQuality of LifeResistance TrainingSleepSurveys and QuestionnairesBlood GlucoseGlycated Hemoglobinhemoglobin A1c protein, human

Identifiers

PMID29465549
PMCPMC5841997
OpenAlexW2790038415

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.