Evidence map›Paper›PMID 29464923›Full record

ArticlePhysiological reports2018

Effect of acute hypoxemia on cerebral blood flow velocity control during lower body negative pressure.

Noud van Helmond, Blair D Johnson, Walter W Holbein, Humphrey G Petersen-Jones, Ronée E Harvey, Sushant M Ranadive, Jill N Barnes, Timothy B Curry, Victor A Convertino, Michael J Joyner

Open access · goldAbstract read
In one paragraph

Article in Physiological reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Static autoregulation in humans.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2024
    Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Impact of environmental stressors on tolerance to hemorrhage in humans.American journal of physiology. Regulatory, integrative and comparative physiology · 2019
    Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Noud van HelmondDepartment of Anesthesiology, Mayo Clinic, Rochester, Minnesota.
Blair D JohnsonCenter for Research and Education in Special Environments, Department of Exercise and Nutrition Sciences, University at Buffalo, Buffalo, New York.
Walter W HolbeinNonin Medical Inc, Plymouth, Minnesota.
Humphrey G Petersen-JonesDepartment of Anesthesiology, Mayo Clinic, Rochester, Minnesota.
Ronée E HarveyMayo Clinic School of Medicine and Science, Mayo Clinic, Rochester, Minnesota.
Sushant M RanadiveDepartment of Anesthesiology, Mayo Clinic, Rochester, Minnesota.
Jill N BarnesDepartment of Kinesiology, University of Wisconsin-Madison, Madison, Wisconsin.
Timothy B CurryDepartment of Anesthesiology, Mayo Clinic, Rochester, Minnesota.
Victor A ConvertinoUS Army Battlefield Health & Trauma Center for Human Integrative Physiology, Fort Sam Houston, Texas.
Michael J JoynerDepartment of Anesthesiology, Mayo Clinic, Rochester, Minnesota.
Mayo Clinic · USNonin Medical (United States) · USUnited States Army Institute of Surgical Research · USUniversity at Buffalo, State University of New York · USUniversity of Wisconsin–Madison · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The ability to maintain adequate cerebral blood flow and oxygenation determines tolerance to central hypovolemia. We tested the hypothesis that acute hypoxemia during simulated blood loss in humans would cause impairments in cerebral blood flow control. Ten healthy subjects (32 ± 6 years, BMI 27 ± 2 kg·m

Indexed as

Cerebrovascular CirculationAdultBlood Flow VelocityHumansHypoxiaLower Body Negative PressureMaleCentral hypovolemiacerebrovascular controlhypoxemiahypoxialower body negative pressureSimulated hemorrhage

Identifiers

PMID29464923
PMCPMC5820424
OpenAlexW2792330401

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.