Trial reportObesity (Silver Spring, Md.)2018
Greater Neonatal Fat-Free Mass and Similar Fat Mass Following a Randomized Trial to Control Excess Gestational Weight Gain.
Trial report in Obesity (Silver Spring, Md.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 7 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 7 syntheses or guidelines pooled it, 49 citations in OpenAlex.
- Pooled it
- Behavior change techniques in pregnancy dietary interventions: a systematic review through the lens of the COM-B model.BMC pregnancy and childbirth · 2025Pooled it
- Systematic review of interventions in early pregnancy among pregnant individuals at risk for hyperglycemia.American journal of obstetrics & gynecology MFM · 2025Pooled it
- Healthy Eating Index Diet Quality in Randomized Weight Loss Trials: A Systematic Review.Journal of the Academy of Nutrition and Dietetics · 2023Pooled it
- Effectiveness of multimodal nutrition interventions during pregnancy to achieve 2009 Institute of Medicine gestational weight gain guidelines: a systematic review and meta-analysis.Annals of medicine · 2021Pooled it
- Pooled it
- Lifestyle Interventions Limit Gestational Weight Gain in Women with Overweight or Obesity: LIFE-Moms Prospective Meta-Analysis.Obesity (Silver Spring, Md.) · 2018Pooled it
- Trial
- LIFE-Moms: effects of multicomponent lifestyle randomized control trial on physical activity during pregnancy in women with overweight and obesity.The international journal of behavioral nutrition and physical activity · 2025Trial
- An eHealth Intervention in Pregnancy on Maternal Body Composition and Subsequent Perinatal Outcomes: A Randomized Trial.Obesity (Silver Spring, Md.) · 2025Trial
- Metabolic Health and Heterogenous Outcomes of Prenatal Interventions: A Secondary Analysis of a Randomized Clinical Trial.JAMA network open · 2025Trial
- The effects of a lifestyle intervention (the HealthyMoms app) during pregnancy on infant body composition: Secondary outcome analysis from a randomized controlled trial.Pediatric obesity · 2022Trial
- A secondary analysis of maternal ultra-processed food intake in women with overweight or obesity and associations with gestational weight gain and neonatal body composition outcomes.Journal of mother and child · 2021Trial
- Increased Visceral Adipose Tissue Without Weight Retention at 59 Weeks Postpartum.Obesity (Silver Spring, Md.) · 2020Trial
- A systematic review of behavioral interventions to improve maternal outcomes for women in the United States at high risk for adverse pregnancy outcomes.medRxiv : the preprint server for health sciences · 2025Article
- Infant body composition trajectories differ by in utero exposure to gestational diabetes mellitus: a prospective cohort from birth to 12 months.The American journal of clinical nutrition · 2025Article
- Early Life Energy Balance: The Development of Infant Energy Expenditure and Intake in the Context of Obesity.Current obesity reports · 2024Review
- The association of higher offspring early-childhood weight gain with prepregnancy metabolic and bariatric surgery.Obesity (Silver Spring, Md.) · 2024Article
- Physical Activity during Pregnancy and Childhood Obesity: Systematic Review and Meta-Analysis.Journal of clinical medicine · 2024Review
- Maternal 24-h movement patterns across pregnancy and postpartum: The LIFE-Moms consortium.Preventive medicine reports · 2024Article
Corrections and comments
- Commented on by
Authors and funding
10 authors at 5 institutions in 1 country.
Funding
Abstract
objectiveThe objective of this study was to determine the effectiveness of controlling maternal gestational weight gain (GWG) in the second and third trimesters on neonate body composition.
methodsTwo hundred ten healthy women with overweight (25 > BMI < 30) or obesity (BMI ≥ 30) were randomly assigned to a lifestyle intervention (LI) program focused on controlling GWG through nutrition and activity behaviors or to usual obstetrical care (UC). Infant fat and fat-free mass (FFM) at birth were measured by using air displacement plethysmography (PEA POD) and by using quantitative magnetic resonance (QMR).
resultsAt baseline, there were no between-group differences in maternal characteristics (mean [SD]): age: 33.8 (4.3) years, weight: 81.9 (13.7) kg, BMI: 30.4 (4.5), and gestational age at randomization: 14.9 (0.8) weeks. GWG was less in the LI group by 1.79 kg (P = 0.003) or 0.0501 kg/wk (P = 0.002). Compared with UC infants, LI infants had greater weight (131 ± 59 g P = 0.03), FFM (98 ± 45 g; P = 0.03) measured by PEA POD, and lean mass (105 ± 38 g; P = 0.006) measured by QMR. Fat mass and percent fat were not significantly different.
conclusionsIntervening in women with overweight and obesity through behaviors promoting healthy diet and physical activity to control GWG resulted in neonates with similar fat and greater FFM.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.