ReviewHepatology international2018
Idiopathic portal hypertension and extrahepatic portal venous obstruction.
Review in Hepatology international, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed, 80 citations in OpenAlex.
- Imaging assessment and interventional management of paediatric portal hypertension: an update.Pediatric radiology · 2026Review
- Gut microbiota analysis in cirrhosis and non-cirrhotic portal hypertension suggests that portal hypertension can be main factor of cirrhosis-specific dysbiosis.Scientific reports · 2025Article
- Case Report: Partial Splenic Artery Embolization for the Treatment of Painful Splenomegaly Secondary to Noncirrhotic Portal Hypertension.Case reports in hepatology · 2025Article
- The effectiveness of endoscopic sclerotherapy in the treatment of esophageal varices in children with prehepatic portal hypertension.Pediatric surgery international · 2024Article
- Management of extensive portal vein thrombosis via thrombolysis and thrombectomy without underlying liver disease: A case report.Clinical case reports · 2024Article
- Non-cirrhotic intrahepatic portal hypertension: Is the gun loaded?Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2024Article
- Clinical features of extrahepatic portal vein obstruction: Myeloproliferative neoplasms eliminate hypersplenic hematologic changes in extrahepatic portal vein obstruction.Intractable & rare diseases research · 2024Article
- [Idiopathic portal hypertension: a case report].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2024Article
- Balloon angioplasty versus stent placement for the treatment of portal vein stenosis in children: a single center experience.Pediatric radiology · 2023Article
- Endovascular treatment of symptomatic hepatic venous outflow obstruction post major liver resection.BMC gastroenterology · 2023Article
- A Rare Case of Extrahepatic Portal Venous Obstruction in a Nine-Year-Old Female and Its Management: A Case Report.Cureus · 2022Article
- Interventional Management of Portal Hypertension in Cancer Patients.Current oncology reports · 2022Review
- A Case of Premenopausal Uterine Leiomyoma, Non-cirrhotic Portal Fibrosis, Hepatic Koch's, a PET Gone Astray-Morphology Antidotes a Confounding Concoction.Iranian journal of pathology · 2022Article
- [Establishment of a nomogram model for predicting bleeding risk based on endoscopic ultrasound and clinical data among patients with liver cirrhosis].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2021Article
- Portal vein thrombosis: A concise review (Review).Experimental and therapeutic medicine · 2021Review
- Current Indications and Long-Term Outcomes of Surgical Portosystemic Shunts in Adults.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2021Article
- Management of a rare case of extra hepatic portal vein obstruction with temporomandibular joint ankylosis and review of literature.Annals of hepato-biliary-pancreatic surgery · 2021Article
- Gastroesophageal varices in a patient presenting with essential thrombocythemia: A case report.World journal of clinical cases · 2021Article
- Review
- Diagnostic challenges in non-cirrhotic portal hypertension - porto sinusoidal vascular disease.World journal of gastroenterology · 2020Review
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIdiopathic portal hypertension (IPH) and extrahepatic portal venous obstruction (EHPVO) are non-cirrhotic vascular causes of portal hypertension (PHT). Variceal bleed and splenomegaly are the commonest presentations.
aimThe present review is intended to provide the existing literature on etiopathogenesis, clinical profile, diagnosis, natural history and management of IPH and EHPVO.
resultsIPH and EHPVO are both characterized by normal hepatic venous pressure gradient, moderate to massive splenomegaly with preserved liver synthetic functions. While the level of block in IPH is presinusoidal, in EHPVO it is at prehepatic level. Infections, autoimmunity, drugs, immunodeficiency and prothrombotic states are possible etiological agents in IPH. Contrastingly in EHPVO, prothrombotic disorders and local factors around the portal vein are the incriminating factors. Diagnosis is often clinical, supported by simple radiological tools. Natural history is defined by episodes of variceal bleed and symptoms related to enlarged spleen. Growth failure, portal biliopathy and minimal hepatic encephalopathy are additional concerns in EHPVO. Long-term survival is reasonably good with endoscopic surveillance; however, parenchymal extinction leading to decompensation is seen in a minority of patients in both the disorders. Surgical shunts revert the complications secondary to PHT. Meso-Rex shunt has become the standard surgery in children with EHPVO.
conclusionThis review gives a detailed summary of these two vascular conditions of liver-IPH and EHPVO. Further research is needed to understand the pathogenesis and natural history of these disorders.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.