Evidence map›Paper›PMID 29464375›Full record

ArticleJournal of neurology2018

Association between marriage and outcomes in patients with acute ischemic stroke.

Qi Liu, Xianwei Wang, Yilong Wang, Chunxue Wang, Xingquan Zhao, Liping Liu, Zixiao Li, Xia Meng, Li Guo, Yongjun Wang

Abstract readMulticenter Study
In one paragraph

Article in Journal of neurology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  6. Marital Failure and Subsequent Heart Failure: A Prospective Study.Journal of the American Heart Association · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Qi LiuDepartment of Neurology, The Second Hospital of Hebei Medical University, No.215 Hepingxilu, Xinhua District, Shijiazhuang, 050000, Hebei, China.
Xianwei WangDepartment of Neurology, Beijing Tiantan Hospital, Capital Medical University, No.6 Tiantanxili, Dongcheng District, Beijing, 100050, China.
Yilong WangDepartment of Neurology, Beijing Tiantan Hospital, Capital Medical University, No.6 Tiantanxili, Dongcheng District, Beijing, 100050, China.
Chunxue WangDepartment of Neurology, Beijing Tiantan Hospital, Capital Medical University, No.6 Tiantanxili, Dongcheng District, Beijing, 100050, China.
Xingquan ZhaoDepartment of Neurology, Beijing Tiantan Hospital, Capital Medical University, No.6 Tiantanxili, Dongcheng District, Beijing, 100050, China.
Liping LiuDepartment of Neurology, Beijing Tiantan Hospital, Capital Medical University, No.6 Tiantanxili, Dongcheng District, Beijing, 100050, China.
Zixiao LiDepartment of Neurology, Beijing Tiantan Hospital, Capital Medical University, No.6 Tiantanxili, Dongcheng District, Beijing, 100050, China.
Xia MengDepartment of Neurology, Beijing Tiantan Hospital, Capital Medical University, No.6 Tiantanxili, Dongcheng District, Beijing, 100050, China.
Li GuoDepartment of Neurology, The Second Hospital of Hebei Medical University, No.215 Hepingxilu, Xinhua District, Shijiazhuang, 050000, Hebei, China. guoli6hb@163.com.
Yongjun WangDepartment of Neurology, Beijing Tiantan Hospital, Capital Medical University, No.6 Tiantanxili, Dongcheng District, Beijing, 100050, China. yongjunwang1962@gmail.com.

Funding

Ministry of Science and Technology 2011BAI08B02Ministry of Science and Technology 2012ZX09303National Key R&D Program of China 2017YFC1310900National Key R&D Program of China 2017YFC1310901
6 · The paper itself

Abstract

backgroundsThe previous studies on the association between marital status and stroke outcomes were rare. Furthermore, the existing studies mostly focused on the protective effect of marriage on survival. We conducted the study to evaluate the association between marital status and adverse stroke outcomes in patients with AIS based on China national stroke registry.

methodsThis was a multicenter, prospective cohort study of patients with AIS. Patients were classified into two groups based on marital status at admission: married and unmarried. The primary outcomes included all-cause mortality, stroke recurrence, combined endpoint, and stroke disability. Stroke disability was defined as modified Rankin Scale of 2-6.

resultsOf 12,118 patients, 1220 were unmarried and 10,898 married. Unmarried patients had higher proportion of 1-year post-stroke events than married patients did. As compared with being unmarried, the adjusted odds ratios with 95% confidence interval of being married for outcomes were as follows: 0.70 (0.58-0.84) for all-cause mortality, 0.78 (0.66-0.91) for stroke recurrence, 0.77 (0.66-0.90) for combined endpoint, and 0.75 (0.65-0.88) for stroke disability. Interactions between marital status and education were significant for all outcomes except for stroke disability.

conclusionsMarital status was associated with all adverse stroke outcomes in patients with acute ischemic stroke, especially in those with middle-school education.

Indexed as

Marital StatusStrokeAgedAged, 80 and overBrain IschemiaCohort StudiesFemaleHospitalizationHumansIncidenceMaleMiddle AgedOdds RatioOutcome Assessment, Health CareRegistriesStatistics, NonparametricAcute ischemic strokeAll-cause deathMarital statusStroke disabilityStroke recurrence

Identifiers

PMID29464375
PMCPMC5878185

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.