Evidence map›Paper›PMID 29464371›Full record

ArticleInternational orthopaedics2018

Risk factor analysis for re-collapse of cemented vertebrae after percutaneous vertebroplasty (PVP) or percutaneous kyphoplasty (PKP).

Yong-Xian Li, Dan-Qing Guo, Shun-Cong Zhang, De Liang, Kai Yuan, Guo-Ye Mo, Da-Xing Li, Hui-Zhi Guo, Yongchao Tang, Pei-Jie Luo

Abstract read
PubMed Publisher
In one paragraph

Article in International orthopaedics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 75 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
75citing papers in PubMed, 7 pooled it
9.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

75 citing papers in PubMed, 7 syntheses or guidelines pooled it, 106 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Risk factors for refracture or new vertebral compression fractures after percutaneous vertebroplasty: a systematic review and meta-analysis.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2025
    Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Pooled it
  8. Trial
  9. Article
  10. Article
  11. Development and validation of a prediction model for vertebral recompression and adjacent vertebral fracture after kyphoplasty in geriatric patients.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Vertebral CT Hounsfield units in postmenopausal women with osteoporotic vertebral compression fracture: identification and validation of reference intervals.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025
    Article

15 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Yong-Xian LiThe First Clinical Academy, Guangzhou University of Chinese Medicine, Guangzhou, 510405, China.
Dan-Qing GuoThe First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, 510407, China.
Shun-Cong ZhangThe First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, 510407, China. spinezsc@126.com.ORCID 0000-0002-3059-2487
De LiangThe First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, 510407, China. 13802757329@139.com.
Kai YuanThe First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, 510407, China.
Guo-Ye MoThe First Clinical Academy, Guangzhou University of Chinese Medicine, Guangzhou, 510405, China.
Da-Xing LiThe First Clinical Academy, Guangzhou University of Chinese Medicine, Guangzhou, 510405, China.
Hui-Zhi GuoThe First Clinical Academy, Guangzhou University of Chinese Medicine, Guangzhou, 510405, China.
Yongchao TangThe First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, 510407, China.
Pei-Jie LuoThe First Clinical Academy, Guangzhou University of Chinese Medicine, Guangzhou, 510405, China.
Guangzhou University of Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeRe-collapse of cemented vertebrae occasionally occurs after percutaneous augmentation. However, the potential risks still remain unclear. Several articles have reported some possible risk factors which were not consistent or comprehensive. This study aimed to make a retrospective review on patients with osteoporotic vertebral compression fracture (OVCF) after percutaneous vertebroplasty (PVP) or percutaneous kyphoplasty (PKP) and to further analyse the risk factors for treated vertebral refracture.

methodsAll patients receiving the PKP/PVP with bilateral approach were retrospectively reviewed from January 2014 to January 2016, among whom 230 patients with single level augmentation (30 in refracture group and 200 in the non-refracture group) were enrolled according to inclusion criteria. The following covariates were reviewed: gender, age, height, weight, body mass index (BMI), bone mineral density (BMD), serum bone turnover markers, surgical parameters including approach, cement volume, anterior height, and Cobb angle restoration. Binary logistic regression analysis was used to determine the relative risk of re-collapse of cemented vertebrae.

resultsRegarding the patient data, weight, BMI, and BMD were of statistical significance in refracture group (P < 0.01), among which only low BMD was a risk factor to cemented vertebral re-collapse (P = 0.022, OR = 4.197). In respect of surgical variables, the better restoration of anterior height and Cobb angle was found in refracture group (P < 0.05), both of which might increase the refracture risk but not be risk factors (P = 0.065, OR = 0.891, and P = 0.937, OR = 0.996, respectively). Besides, less injected cement (3.30 ± 0.84 ml vs 4.46 ± 1.10 ml, P = 0.000, OR = 19.433) and PKP (P = 0.007, OR = 13.332) significantly boosted the potential risk of refracture (P < 0.001).

conclusionPatients with low BMD, or undergoing PKP, or receiving a low volume of injected cement might have a high risk of re-collapse in surgical vertebrae.

Indexed as

AgedAged, 80 and overBone CementsBone DensityFemaleFractures, CompressionHumansKyphoplastyMaleMiddle AgedOsteoporotic FracturesRecurrenceRetrospective StudiesRisk FactorsSpinal FracturesTreatment OutcomeBone CementsOsteoporotic vertebral compression fracturesPercutaneous kyphoplastyPercutaneous vertebroplastyRe-collapseRisk factors

Identifiers

PMID29464371
OpenAlexW2793094515

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.