ArticleClinical oral investigations2018
Dentinal tubule obliteration using toothpastes containing sodium trimetaphosphate microparticles or nanoparticles.
Article in Clinical oral investigations, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 46 citations in OpenAlex.
- Development of a cycling protocol for the in vitro assessment of enamel erosion and the effect of a fluoridated mouthrinse containing micrometric- and nano-sized trimetaphosphate on erosion prevention.Clinical oral investigations · 2025Trial
- Coadministration of fluoride, trimetaphosphate, and quercetin reduces dentin erosive wear in vitro.Clinical oral investigations · 2026Article
- Calcium ionic replacement in sodium trimetaphosphate particles: a novel strategy for bone tissue engineering.Journal of materials science. Materials in medicine · 2026Article
- Analysis of dentin wear and biological properties promoted by experimental inoffice desensitizing materials.BMC oral health · 2024Article
- Synthesis, Characterization, and Evaluation of the Antimicrobial Effects and Cytotoxicity of a Novel Nanocomposite Based on Polyamide 6 and Trimetaphosphate Nanoparticles Decorated with Silver Nanoparticles.Antibiotics (Basel, Switzerland) · 2024Article
- Influence of Er:YAG and ND:YAG laser irradiation and fluoride application on surface roughness and dentin surface wear after erosive challenge - An in vitro study.Journal of clinical and experimental dentistry · 2024Article
- Effect of treatment with phosphate, casein phosphopeptide and fluoride on the remineralization: in vitro study.Brazilian oral research · 2024Article
- Calcium Trimetaphosphate-Loaded Electrospun Poly(Ester Urea) Nanofibers for Periodontal Tissue Engineering.Journal of functional biomaterials · 2023Article
- In vitro dentin permeability and tubule occlusion of experimental in-office desensitizing materials.Clinical oral investigations · 2023Article
- In vitro effect of low-fluoride toothpaste supplemented with sodium trimetaphosphate, xylitol, and erythritol on enamel demineralization.Journal of applied oral science : revista FOB · 2023Article
- Effect of different toothpastes on permeability and roughness of eroded dentin.Acta odontologica latinoamericana : AOL · 2022Article
- Novel pulp capping material based on sodium trimetaphosphate: synthesis, characterization, and antimicrobial properties.Journal of applied oral science : revista FOB · 2022Article
- In vitro effect of toothpaste with low fluoride combined with sodium trimetaphosphate on dentine erosion.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2021Article
- Combined effect of casein phosphopeptide-amorphous calcium phosphate and sodium trimetaphosphate on the prevention of enamel demineralization and dental caries: an in vitro study.Clinical oral investigations · 2021Article
- Hydraulic conductance of dentin after treatment with fluoride toothpaste containing sodium trimetaphosphate microparticles or nanoparticles.Clinical oral investigations · 2021Article
- The Stability of Dentin Surface Biobarrier Consisting of Mesoporous Delivery System on Dentinal Tubule Occlusion and Streptococcus Mutans Biofilm Inhibition.International journal of nanomedicine · 2021Article
- Acidic Monetite Complex Paste with Bleaching Property for In-depth Occlusion of Dentinal Tubules.International journal of nanomedicine · 2021Article
- Applications of nano-materials in diverse dentistry regimes.RSC advances · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
objectivesThis in vitro study evaluated the effect of microparticles (TMPmicro) or nanoparticles (TMPnano) TMP associated with fluoride (F) in toothpaste formulations on the obliteration of dentinal tubules (DT). MATERIALS AND
methodsThe dentinal tubules of bovine dentin blocks were unobstructed by immersion in 37% phosphoric acid solution. Blocks (n = 20/group) underwent mechanical brushing (2×/day) during 7 days with toothpastes: placebo, 1100 ppm F, and 1100 with 3% TMPmicro or 3% TMPnano. After that, ten blocks of each group were immersed in citric acid (pH 3.2) for 1 min. The number, diameter and area of unobstructed DT, atomic % of chemical elements from precipitates, and the mineral concentration were quantified. Data were submitted to two-way ANOVA, followed by Student-Newman-Keuls test (P < 0.05).
resultsToothpastes containing TMPmicro and TMPnano promoted greater obliteration of DT and greater mineral concentration compared to other groups (P < 0.05). Placebo and 1100 ppm F group presented similar obliteration but 1100 ppm F group promoted higher mineral concentration. Higher Ca/P ratios were observed in groups treated with TMP; the acid challenge reduced Ca/P ratio for all groups. The atomic % of C and N was significantly lower for TMP toothpastes before acid challenge, but increased afterwards.
conclusionsIt was concluded that the addition of TMPmicro or TMPnano to F toothpastes produced greater obliteration of dentinal tubules and higher mineral concentration when compared with 1100 ppm F. CLINICAL RELEVANCE: By the addition of TMP, fluoride toothpastes may occlude the dentinal tubules, with potential to reduce dentin hypersensitivity.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.