Evidence map›Paper›PMID 29464270›Full record

ArticleNaunyn-Schmiedeberg's archives of pharmacology2018

Diabetes modifies the role of prostanoids and potassium channels which regulate the hypereactivity of the rabbit renal artery to BNP.

José M Centeno, Luis Miranda-Gómez, Mikahela A López-Morales, Teresa Jover-Mengual, María C Burguete, Vannina G Marrachelli, María Castelló-Ruiz, Alicia Aliena-Valero, Enrique Alborch, Francisco J Miranda

Open access · greenAbstract read
PubMed Publisher
In one paragraph

Article in Naunyn-Schmiedeberg's archives of pharmacology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

José M CentenoUnidad Mixta de Investigación Cerebrovascular (UMIC), Departamento de Fisiología, Universidad de Valencia-Instituto de Investigación Sanitaria La Fe, Valencia, Spain.
Luis Miranda-GómezUnidad Mixta de Investigación Cerebrovascular (UMIC), Departamento de Fisiología, Universidad de Valencia-Instituto de Investigación Sanitaria La Fe, Valencia, Spain.
Mikahela A López-MoralesUnidad Mixta de Investigación Cerebrovascular (UMIC), Departamento de Fisiología, Universidad de Valencia-Instituto de Investigación Sanitaria La Fe, Valencia, Spain.
Teresa Jover-MengualUnidad Mixta de Investigación Cerebrovascular (UMIC), Departamento de Fisiología, Universidad de Valencia-Instituto de Investigación Sanitaria La Fe, Valencia, Spain.
María C BurgueteUnidad Mixta de Investigación Cerebrovascular (UMIC), Departamento de Fisiología, Universidad de Valencia-Instituto de Investigación Sanitaria La Fe, Valencia, Spain.
Vannina G MarrachelliUnidad Mixta de Investigación Cerebrovascular (UMIC), Departamento de Fisiología, Universidad de Valencia-Instituto de Investigación Sanitaria La Fe, Valencia, Spain.
María Castelló-RuizDepartamento de Biología Celular, Biología Funcional y Antropología Física, Universidad de Valencia, Valencia, Spain.
Alicia Aliena-ValeroUnidad Mixta de Investigación Cerebrovascular (UMIC), Departamento de Fisiología, Universidad de Valencia-Instituto de Investigación Sanitaria La Fe, Valencia, Spain.
Enrique AlborchUnidad Mixta de Investigación Cerebrovascular (UMIC), Departamento de Fisiología, Universidad de Valencia-Instituto de Investigación Sanitaria La Fe, Valencia, Spain.
Francisco J MirandaUnidad Mixta de Investigación Cerebrovascular (UMIC), Departamento de Fisiología, Universidad de Valencia-Instituto de Investigación Sanitaria La Fe, Valencia, Spain. francisco.j.miranda@uv.es.
Universitat de València · ESInstituto de Investigación Sanitaria La Fe · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diabetic nephropathy is associated with increased risk of cardiovascular disease. B-type natriuretic peptide (BNP) plays an important role in cardiovascular pathophysiology and therapeutics. The aim of the present study was to investigate the influence of experimental diabetes on the mechanisms that regulate the relaxant response of the rabbit renal artery to BNP. Arterial relaxations to BNP were enhanced in diabetic rabbits. Indomethacin enhanced BNP-induced relaxation in control rabbits but showed no effect in diabetic rabbits. BNP-induced release of thromboxane A

Indexed as

AnimalsDiabetes Mellitus, ExperimentalMaleNatriuretic Peptide, BrainPotassium ChannelsProstaglandinsRabbitsRenal ArteryVasodilationNatriuretic Peptide, BrainPotassium ChannelsProstaglandinsB-type natriuretic peptideDiabetesPotassium channelsProstanoidsRenal artery

Identifiers

PMID29464270
OpenAlexW2789882007

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.