Evidence map›Paper›PMID 29464007›Full record

ArticleTheranostics2018

Diagnosis of LVAD Thrombus using a High-Avidity Fibrin-Specific

Grace Cui, Walter J Akers, Michael J Scott, Michael Nassif, John S Allen, Anne H Schmieder, Krishna S Paranandi, Akinobu Itoh, Dmitry D Beyder, Samuel Achilefu and 2 more

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Grace CuiDivision of Cardiology, Washington University School of Medicine, St. Louis, MO.
Walter J AkersMallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO.
Michael J ScottDivision of Cardiology, Washington University School of Medicine, St. Louis, MO.
Michael NassifDivision of Cardiology, Washington University School of Medicine, St. Louis, MO.
John S AllenDivision of Cardiology, Washington University School of Medicine, St. Louis, MO.
Anne H SchmiederDivision of Cardiology, Washington University School of Medicine, St. Louis, MO.
Krishna S ParanandiDivision of Cardiology, Washington University School of Medicine, St. Louis, MO.
Akinobu ItohDivision of Cardiothoracic Surgery, Washington University School of Medicine, St. Louis, MO.
Dmitry D BeyderBarnes-Jewish Hospital, St. Louis, MO.
Samuel AchilefuMallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO.
Gregory A EwaldDivision of Cardiology, Washington University School of Medicine, St. Louis, MO.
Gregory M LanzaDivision of Cardiology, Washington University School of Medicine, St. Louis, MO.
Washington University in St. Louis · USMallinckrodt (United States) · USBarnes-Jewish Hospital · US

Funding

Project 2 - Radiation-Induced Treatment of Multiple Myeloma using NanoparticlesU54CA199092 · NCI · WASHINGTON UNIVERSITY · PI ACHILEFU, SAMUEL · 2015 to 2019
$11.5M
Theranostic Approach to Asthma Using Anti-Angiogenic NanomedicineR01HL113392 · NHLBI · WASHINGTON UNIVERSITY · PI LANZA, GREGORY M, WAGNER, ELIZABETH · 2012 to 2016
$3.3M
NANOPHOTOSENSITIZERS FOR REGENERATIVE PHOTOTHERAPY OF TUMORSR01EB021048 · NIBIB · WASHINGTON UNIVERSITY · PI ACHILEFU, SAMUEL · 2015 to 2020
$2.3M
DIAGNOSIS OF LEFT VENTRICULAR ASSIST DEVICE INTRAPUMP THROMBOSISR01HL122471 · NHLBI · WASHINGTON UNIVERSITY · PI ACHILEFU, SAMUEL, LANZA, GREGORY M · 2015 to 2018
$1.8M
NCI NIH HHS U54 CA199092NHLBI NIH HHS HHSN268201400042CNHLBI NIH HHS R01 HL113392NHLBI NIH HHS R01 HL122471NIBIB NIH HHS R01 EB021048
6 · The paper itself

Abstract

Treatment of advanced heart failure with implantable LVADs is increasing, driven by profound unmet patient need despite potential serious complications: bleeding, infection, and thrombus. The experimental objective was to develop a sensitive imaging approach to assess early thrombus accumulation in LVADs under operational high flow and high shear rates.

Indexed as

AnimalsFibrinHalf-LifeHeart-Assist DevicesHeart FailureHumansMiceProtein BindingRecombinant ProteinsStaining and LabelingTechnetiumThrombosisFibrinRecombinant ProteinsTechnetiumfibrinLVADnuclear imagingtechnetiumthrombosis

Identifiers

PMID29464007
PMCPMC5817118
OpenAlexW2789488368

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.