Evidence map›Paper›PMID 29464006›Full record

ArticleTheranostics2018

Delivery of Sonic Hedgehog Gene Repressed Irradiation-induced Cellular Senescence in Salivary Glands by Promoting DNA Repair and Reducing Oxidative Stress.

Bo Hai, Qingguo Zhao, Michael A Deveau, Fei Liu

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 1 synthesis or guideline pooled it, 45 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Anti-aging effect of Hedgehog signaling.Experimental & molecular medicine · 2026
    Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. Review
  12. Salivary Gland Bioengineering.Bioengineering (Basel, Switzerland) · 2023
    Review
  13. Review
  14. Article
  15. Gene Therapeutic Delivery to the Salivary Glands.Advances in experimental medicine and biology · 2023
    Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Bo HaiInstitute for Regenerative Medicine, Molecular and Cellular Medicine Department, College of Medicine, Texas A&M University Health Science Center, College Station, Texas 77843, USA.
Qingguo ZhaoInstitute for Regenerative Medicine, Molecular and Cellular Medicine Department, College of Medicine, Texas A&M University Health Science Center, College Station, Texas 77843, USA.
Michael A DeveauDepartment of Small Animal Clinical Sciences, College of Veterinary Medicine & Biomedical Sciences, Texas A&M University, College Station, Texas 77843, USA.
Fei LiuInstitute for Regenerative Medicine, Molecular and Cellular Medicine Department, College of Medicine, Texas A&M University Health Science Center, College Station, Texas 77843, USA.
Texas A&M Health Science Center · USTexas College · US

Funding

Mechanisms of Hedgehog Mediated Rescue of Radiation-induced HyposalivationR01DE022975 · NIDCR · TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR · PI LIU, FEI · 2012 to 2015
$1.4M
NIDCR NIH HHS R01 DE022975
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdenoviridaeAnimalsCellular SenescenceDisease Models, AnimalDNA RepairGenetic TherapyGenetic VectorsHedgehog ProteinsMiceOxidative StressRadiation InjuriesSalivary Gland DiseasesSalivary GlandsTransduction, GeneticTreatment OutcomeXerostomiaHedgehog ProteinsShh protein, mousecellular senescenceDNA repairHedgehog signalingIrradiation-induced hyposalivationoxidative stress

Identifiers

PMID29464006
PMCPMC5817117
OpenAlexW2791177725

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.