Evidence map›Paper›PMID 29463992›Full record

ArticleTheranostics2018

Investigating the Intracellular Behaviors of Liposomal Nanohybrids

Dan Zhu, Zhuyuan Wang, Shenfei Zong, Yizhi Zhang, Chen Chen, Ruohu Zhang, Binfeng Yun, Yiping Cui

Abstract read
In one paragraph

Article in Theranostics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Dan ZhuAdvanced Photonics Center, Southeast University, 2# Sipailou, Nanjing 210096, Jiangsu, China.
Zhuyuan WangAdvanced Photonics Center, Southeast University, 2# Sipailou, Nanjing 210096, Jiangsu, China.
Shenfei ZongAdvanced Photonics Center, Southeast University, 2# Sipailou, Nanjing 210096, Jiangsu, China.
Yizhi ZhangAdvanced Photonics Center, Southeast University, 2# Sipailou, Nanjing 210096, Jiangsu, China.
Chen ChenAdvanced Photonics Center, Southeast University, 2# Sipailou, Nanjing 210096, Jiangsu, China.
Ruohu ZhangAdvanced Photonics Center, Southeast University, 2# Sipailou, Nanjing 210096, Jiangsu, China.
Binfeng YunAdvanced Photonics Center, Southeast University, 2# Sipailou, Nanjing 210096, Jiangsu, China.
Yiping CuiAdvanced Photonics Center, Southeast University, 2# Sipailou, Nanjing 210096, Jiangsu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The recent proposition to combine liposomes with nanoparticles presents great opportunities to develop multifunctional drug delivery platforms. Although impressive progress has been made, attempts to elucidate the role nanoparticles play in the integral nanohybrids are still rather limited. Here, using surface-enhanced Raman scattering (SERS) technique, we investigate the influence of metal nanoparticles on the liposomal properties, ranging from drug release to intracellular movement. Specifically, we prepared SERS-active nanohybrids by attaching metal nanoparticles to liposomes and employed SERS signals to explore the intracellular behavior of the nanohybrids. Once deposited on the cell membrane, the nanohybrids entered tumor cells

Indexed as

CytoplasmDrug CarriersEndocytosisHumansLiposomesLysosomesMetal NanoparticlesSpectrum Analysis, RamanTumor Cells, CulturedDrug CarriersLiposomesintracellular behavior.liposomesmetal nanoparticlesnanohybridsSERS

Identifiers

PMID29463992
PMCPMC5817103

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.