Evidence map›Paper›PMID 29463950›Full record

Trial reportBehavioural neurology2017

Efficacy of a Computer-Assisted Cognitive Rehabilitation Intervention in Relapsing-Remitting Multiple Sclerosis Patients: A Multicenter Randomized Controlled Trial.

Lambros Messinis, Grigorios Nasios, Mary H Kosmidis, Petros Zampakis, Sonia Malefaki, Katerina Ntoskou, Anastasia Nousia, Christos Bakirtzis, Nikolaos Grigoriadis, Philippos Gourzis and 1 more

Abstract readMulticenter StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Behavioural neurology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Virtual reality for multiple sclerosis rehabilitation.The Cochrane database of systematic reviews · 2025
    Pooled it
  2. Pooled it
  3. Memory rehabilitation for people with multiple sclerosis.The Cochrane database of systematic reviews · 2021
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Lambros MessinisNeuropsychology Section, Department of Neurology, University of Patras Medical School, 26504 Patras, Greece.ORCID 0000-0002-3216-9025
Grigorios NasiosDepartment of Speech and Language Therapy, Higher Educational Institute of Epirus, Ioannina, Ioannina, Greece.ORCID 0000-0001-7495-6863
Mary H KosmidisLab of Cognitive Neuroscience, School of Psychology, Aristotle University of Thessaloniki, Thessaloniki, Greece.
Petros ZampakisDepartment of Radiology, University of Patras Medical School, 26504 Patras, Greece.
Sonia MalefakiDepartment of Mechanical Engineering & Aeronautics, University of Patras, 26504 Patras, Greece.
Katerina NtoskouRehabilitation Unit for Patients with Spinal Cord Injury, "Demetrios and Vera Sfikas", Department of Medicine, University of Patras, 26504 Patras, Greece.
Anastasia NousiaDepartment of Speech and Language Therapy, Higher Educational Institute of Epirus, Ioannina, Ioannina, Greece.
Christos BakirtzisB'Department of Neurology and the MS Center, AHEPA University Hospital of Thessaloniki, Thessaloniki, Greece.
Nikolaos GrigoriadisB'Department of Neurology and the MS Center, AHEPA University Hospital of Thessaloniki, Thessaloniki, Greece.ORCID 0000-0003-4706-4637
Philippos GourzisDepartment of Psychiatry, University Hospital of Patras and University of Patras Medical School, 26504 Patras, Greece.ORCID 0000-0003-2001-4584
Panagiotis PapathanasopoulosUniversity of Patras Medical School, 26504 Patras, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cognitive impairment is frequently encountered in multiple sclerosis (MS) affecting between 40-65% of individuals, irrespective of disease duration and severity of physical disability. In the present multicenter randomized controlled trial, fifty-eight clinically stable RRMS patients with mild to moderate cognitive impairment and relatively low disability status were randomized to receive either computer-assisted (RehaCom) functional cognitive training with an emphasis on episodic memory, information processing speed/attention, and executive functions for 10 weeks (IG;

Indexed as

Outcome Assessment, Health CareAdultAttentionCognitive DysfunctionCognitive RemediationExecutive FunctionFemaleHumansMaleMemoryMiddle AgedMultiple Sclerosis, Relapsing-RemittingTherapy, Computer-Assisted

Identifiers

PMID29463950
PMCPMC5804109

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.