Evidence map›Paper›PMID 29463868›Full record

ArticleScientific reports2018

CD38 promotes pristane-induced chronic inflammation and increases susceptibility to experimental lupus by an apoptosis-driven and TRPM2-dependent mechanism.

Sonia García-Rodríguez, Antonio Rosal-Vela, Davide Botta, Luz M Cumba Garcia, Esther Zumaquero, Verónica Prados-Maniviesa, Daniela Cerezo-Wallis, Nicola Lo Buono, José-Ángel Robles-Guirado, Salvador Guerrero and 9 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
2.5field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 32 citations in OpenAlex.

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  13. CD38 Deficiency Ameliorates Chronic Graft-Frontiers in immunology · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 5 institutions in 4 countries.

Sonia García-RodríguezDepartment of Cellular Biology and Immunology, IPBLN-CSIC, Granada, Spain.
Antonio Rosal-VelaDepartment of Cellular Biology and Immunology, IPBLN-CSIC, Granada, Spain.
Davide BottaDepartment of Microbiology, UAB, Birmingham, Alabama, USA.ORCID 0000-0003-3926-0662
Luz M Cumba GarciaDepartment of Cellular Biology and Immunology, IPBLN-CSIC, Granada, Spain.
Esther ZumaqueroDepartment of Microbiology, UAB, Birmingham, Alabama, USA.
Verónica Prados-ManiviesaDepartment of Cellular Biology and Immunology, IPBLN-CSIC, Granada, Spain.
Daniela Cerezo-WallisDepartment of Cellular Biology and Immunology, IPBLN-CSIC, Granada, Spain.
Nicola Lo BuonoDepartment of Cellular Biology and Immunology, IPBLN-CSIC, Granada, Spain.ORCID 0000-0001-5538-6869
José-Ángel Robles-GuiradoDepartment of Cellular Biology and Immunology, IPBLN-CSIC, Granada, Spain.
Salvador GuerreroFlow Cytometry Unit, IPBLN-CSIC, Granada, Spain.
Elena González-ParedesDepartment of Cellular Biology and Immunology, IPBLN-CSIC, Granada, Spain.
Eduardo Andrés-LeónBioinformatics Unit, IPBLN-CSIC, Granada, Spain.ORCID 0000-0002-0621-9914
Ángel CorbíDepartment of Molecular Microbiology and Infection Biology, CIB-CSIC, Madrid, Spain.
Matthias MackDepartment of Internal Medicine II, Nephrology, Regensburg University Medical Center, Regensburg, Germany.
Friedrich Koch-NolteInstitute of Immunology, University Medical Center Eppendorf-Hamburg, Hamburg, Germany.
Ramón MerinoDepartment of Molecular and Cellular Signalling, IBBTEC-CSIC-UC, Santander, Spain.
Mercedes ZubiaurDepartment of Cellular Biology and Immunology, IPBLN-CSIC, Granada, Spain.
Frances E LundDepartment of Microbiology, UAB, Birmingham, Alabama, USA.
Jaime SanchoDepartment of Cellular Biology and Immunology, IPBLN-CSIC, Granada, Spain. granada@ipb.csic.es.ORCID 0000-0003-3852-7951
Consejo Superior de Investigaciones Científicas · ESInstituto de Biomedicina y Biotecnología de Cantabria · ESMayo Clinic · USUniversität Hamburg · DEUniversity Hospital Regensburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, we investigated the role of CD38 in a pristane-induced murine model of lupus. CD38-deficient (Cd38

Indexed as

ApoptosisADP Ribose TransferasesADP-ribosyl Cyclase 1AnimalsDisease Models, AnimalDisease SusceptibilityImmunologic FactorsImmunosuppressive AgentsLeukocytesLupus Erythematosus, CutaneousMembrane GlycoproteinsMiceTerpenesTRPM Cation ChannelsADP Ribose TransferasesADP-ribosyl Cyclase 1Art2a protein, mouseCd38 protein, mouseImmunologic FactorsImmunosuppressive AgentsMembrane GlycoproteinspristaneTerpenesTRPM2 protein, mouseTRPM Cation Channels

Identifiers

PMID29463868
PMCPMC5820326
OpenAlexW2797013432

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.