ArticleProceedings of the National Academy of Sciences of the United States of America2018
NLR surveillance of essential SEC-9 SNARE proteins induces programmed cell death upon allorecognition in filamentous fungi.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.
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Who cites it
48 citing papers in PubMed, 96 citations in OpenAlex.
- NOD-Like Receptor Genes Undergo Diversity-Enhancing Evolution in a Fungal Species Complex.Genome biology and evolution · 2026Article
- Regulated cell death in fungi from a comparative immunology perspective.Cell death and differentiation · 2026Review
- The heat-ramp method to study regulated cell death in a pathogenic yeastbioRxiv : the preprint server for biology · 2026Article
- Genomic organization, domain assortments, and nucleotide-binding domain diversity of NLR proteins in Sordariales fungi.PLoS genetics · 2025Article
- Identification of regions required for allelic specificity at the cell wall remodeling allorecognition checkpoint in Neurospora crassa.Genetics · 2025Article
- The N-terminal domains of NLR immune receptors exhibit structural and functional similarities across divergent plant lineages.The Plant cell · 2024Article
- What are the 100 most cited fungal genera?Studies in mycology · 2024Article
- A comprehensive review of soybean RNL and TIR domain proteins.Plant molecular biology · 2024Review
- The Narrow Footprint of Ancient Balancing Selection Revealed by Heterokaryon Incompatibility Genes in Aspergillus fumigatus.Molecular biology and evolution · 2024Article
- Evolutionary trajectory of pattern recognition receptors in plants.Nature communications · 2024Article
- het-B allorecognition in Podospora anserina is determined by pseudo-allelic interaction of genes encoding a HET and lectin fold domain protein and a PII-like protein.PLoS genetics · 2024Article
- Evolutionary insights and functional diversity of gasdermin family proteins and homologs in microorganisms.Frontiers in immunology · 2024Review
- Article
- Lineage-specific genes are clustered with HET-domain genes and respond to environmental and genetic manipulations regulating reproduction in Neurospora.PLoS genetics · 2023Article
- Taking the lead: NLR immune receptor N-terminal domains execute plant immune responses.The New phytologist · 2023Review
- Emergence of the fungal immune system.iScience · 2023Review
- Physiological variations in hypovirus-infected wild and model long-term laboratory strains ofFrontiers in microbiology · 2023Article
- Exploring a diverse world of effector domains and amyloid signaling motifs in fungal NLR proteins.PLoS computational biology · 2022Article
- Article
- Prokaryotic innate immunity through pattern recognition of conserved viral proteins.Science (New York, N.Y.) · 2022Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
Abstract
In plants and metazoans, intracellular receptors that belong to the NOD-like receptor (NLR) family are major contributors to innate immunity. Filamentous fungal genomes contain large repertoires of genes encoding for proteins with similar architecture to plant and animal NLRs with mostly unknown function. Here, we identify and molecularly characterize patatin-like phospholipase-1 (PLP-1), an NLR-like protein containing an N-terminal patatin-like phospholipase domain, a nucleotide-binding domain (NBD), and a C-terminal tetratricopeptide repeat (TPR) domain. PLP-1 guards the essential SNARE protein SEC-9; genetic differences at
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.