Evidence map›Paper›PMID 29463678›Full record

ArticleThe Journal of biological chemistry2018

Structural basis of sterol binding and transport by a yeast StARkin domain.

Julian-Alexander Jentsch, Irene Kiburu, Kalpana Pandey, Michael Timme, Trudy Ramlall, Bodo Levkau, Jin Wu, David Eliezer, Olga Boudker, Anant K Menon

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it, 56 citations in OpenAlex.

  1. Stay in touch with the endoplasmic reticulum.Science China. Life sciences · 2024
    Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Cholesterol Transport to the Endoplasmic Reticulum.Cold Spring Harbor perspectives in biology · 2023
    Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. ER-PM Contact Sites - SNARING Actors in Emerging Functions.Frontiers in cell and developmental biology · 2021
    Review
  14. Review
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 3 countries.

Julian-Alexander JentschFrom the Departments of Biochemistry and.
Irene KiburuPhysiology and Biophysics and.
Kalpana PandeyFrom the Departments of Biochemistry and.
Michael TimmeFrom the Departments of Biochemistry and.
Trudy RamlallFrom the Departments of Biochemistry and.
Bodo LevkauInstitute for Pathophysiology, West German Heart and Vascular Centre, University Hospital Essen, 45122 Essen, Germany.
Jin WuFrom the Departments of Biochemistry and.
David EliezerFrom the Departments of Biochemistry and dae2005@med.cornell.edu.
Olga BoudkerPhysiology and Biophysics and olb2003@med.cornell.edu.
Anant K MenonFrom the Departments of Biochemistry and akm2003@med.cornell.edu.
West German Heart and Vascular Center Essen · DECornell University · USInstitute of Molecular Biology and Biophysics · RU

Funding

The structural dynamics of a glutamate transporter homologueR37NS085318 · NINDS · WEILL MEDICAL COLL OF CORNELL UNIV · PI BOUDKER, OLGA · 2014 to 2020
$4.3M
Structure and Function of Alpha-SynucleinR37AG019391 · NIA · WEILL MEDICAL COLL OF CORNELL UNIV · PI ELIEZER, DAVID · 2010 to 2019
$3.4M
Structure and Function of ComplexinR01GM117518 · NIGMS · WEILL MEDICAL COLL OF CORNELL UNIV · PI ELIEZER, DAVID · 2016 to 2019
$1.3M
NIA NIH HHS R37 AG019391NIGMS NIH HHS R01 GM117518NINDS NIH HHS R37 NS085318
6 · The paper itself

Abstract

The StARkin superfamily comprises proteins with steroidogenic acute regulatory protein-related lipid transfer (StART) domains that are implicated in intracellular, non-vesicular lipid transport. A new family of membrane-anchored StARkins was recently identified, including six members, Lam1-Lam6, in the yeast

Indexed as

AntiportersBiological Transport, ActiveProtein DomainsSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsSterolsAntiportersSaccharomyces cerevisiae ProteinsSterolscholesterolcholesterol-binding proteindehydroergosterolendoplasmic reticulum (ER)fluorescence resonance energy transfer (FRET)Lam4lipid transportmembrane contact siteoxysterolStART domain

Identifiers

PMID29463678
PMCPMC5900764
OpenAlexW2788633957

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.