ArticlemBio2018
Microbial Functional Gene Diversity Predicts Groundwater Contamination and Ecosystem Functioning.
Article in mBio, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed.
- Microbial ecology of shallow groundwater ecosystems.Nature reviews. Microbiology · 2026Review
- Multilayered Human Activities Shape the Microbial Communities of Groundwater-Dependent Ecosystems on an Arid Oceanic Island.Microbial ecology · 2026Article
- Modest functional diversity decline and pronounced composition shifts of microbial communities in a mixed waste-contaminated aquifer.Microbiome · 2025Article
- Effects of Environmental Chemical Pollutants on Microbiome Diversity: Insights from Shotgun Metagenomics.Toxics · 2025Article
- Article
- Moving beyond species: fungal function in house dust provides novel targets for potential indicators of mold growth in homes.Microbiome · 2024Article
- Environmental stress mediates groundwater microbial community assembly.Nature microbiology · 2024Article
- A bacterial sensor taxonomy across earth ecosystems for machine learning applications.mSystems · 2024Article
- Microcystis blooms caused the decreasing richness of and interactions between free-living microbial functional genes in Lake Taihu, China.FEMS microbiology ecology · 2024Article
- Potential applications of microbial genomics in nuclear non-proliferation.Frontiers in microbiology · 2024Review
- Ecosystems monitoring powered by environmental genomics: A review of current strategies with an implementation roadmap.Molecular ecology · 2021Review
- Disentangling Responses of the Subsurface Microbiome to Wetland Status and Implications for Indicating Ecosystem Functions.Microorganisms · 2021Article
- Mechanism Across Scales: A Holistic Modeling Framework Integrating Laboratory and Field Studies for Microbial Ecology.Frontiers in microbiology · 2021Article
- In-field bioreactors demonstrate dynamic shifts in microbial communities in response to geochemical perturbations.PloS one · 2020Article
- A general framework for quantitatively assessing ecological stochasticity.Proceedings of the National Academy of Sciences of the United States of America · 2019Article
- Functional Gene Array-Based Ultrasensitive and Quantitative Detection of Microbial Populations in Complex Communities.mSystems · 2019Article
- Article
- Analysis of uranium removal capacity of anaerobic granular sludge bacterial communities under different initial pH conditions.Environmental science and pollution research international · 2019Article
- Impact of hydrologic boundaries on microbial planktonic and biofilm communities in shallow terrestrial subsurface environments.FEMS microbiology ecology · 2018Review
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
24 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Contamination from anthropogenic activities has significantly impacted Earth's biosphere. However, knowledge about how environmental contamination affects the biodiversity of groundwater microbiomes and ecosystem functioning remains very limited. Here, we used a comprehensive functional gene array to analyze groundwater microbiomes from 69 wells at the Oak Ridge Field Research Center (Oak Ridge, TN), representing a wide pH range and uranium, nitrate, and other contaminants. We hypothesized that the functional diversity of groundwater microbiomes would decrease as environmental contamination (e.g., uranium or nitrate) increased or at low or high pH, while some specific populations capable of utilizing or resistant to those contaminants would increase, and thus, such key microbial functional genes and/or populations could be used to predict groundwater contamination and ecosystem functioning. Our results indicated that functional richness/diversity decreased as uranium (but not nitrate) increased in groundwater. In addition, about 5.9% of specific key functional populations targeted by a comprehensive functional gene array (GeoChip 5) increased significantly (
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.