Evidence map›Paper›PMID 29463653›Full record

ArticlemBio2018

Efficient and Scalable Precision Genome Editing in

Kelsi Penewit, Elizabeth A Holmes, Kathyrn McLean, Mingxin Ren, Adam Waalkes, Stephen J Salipante

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in mBio, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 41 papers.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 67 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. ThemBio · 2025
    Article
  5. Article
  6. A diverse single-stranded DNA-annealing protein library enables efficient genome editing across bacterial phyla.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Toolbox of Characterized Genetic Parts forACS synthetic biology · 2024
    Article
  13. GEO dataset mining analysis reveals novelFrontiers in molecular biosciences · 2024
    Article
  14. CRISPR-Based Gene Editing inPharmaceuticals (Basel, Switzerland) · 2023
    Review
  15. Adaptive Laboratory Evolution ofAntibiotics (Basel, Switzerland) · 2023
    Article
  16. Autolysin-mediated peptidoglycan hydrolysis is required for the surface display ofProceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  17. Infection and immunity · 2023
    Article
  18. Recombineering in Non-Model Bacteria.Current protocols · 2022
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Kelsi PenewitDepartment of Laboratory Medicine, University of Washington, Seattle, Washington, USA.
Elizabeth A HolmesDepartment of Laboratory Medicine, University of Washington, Seattle, Washington, USA.
Kathyrn McLeanDepartment of Laboratory Medicine, University of Washington, Seattle, Washington, USA.
Mingxin RenDepartment of Bioengineering, University of Washington, Seattle, Washington, USA.
Adam WaalkesDepartment of Laboratory Medicine, University of Washington, Seattle, Washington, USA.
Stephen J SalipanteDepartment of Laboratory Medicine, University of Washington, Seattle, Washington, USA stevesal@uw.edu.
University of Washington · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Recombination, GeneticClustered Regularly Interspaced Short Palindromic RepeatsCRISPR-Associated Protein 9Gene EditingHumansRecombinasesStaphylococcal InfectionsStaphylococcus aureusCRISPR-Associated Protein 9RecombinasesCas9CRISPRgenetic engineeringgenome editingmutSrecombineeringStaphylococcus aureus

Identifiers

PMID29463653
PMCPMC5821094
OpenAlexW2793296961

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.