Evidence map›Paper›PMID 29463648›Full record

ArticleMolecular and cellular biology2018

Id2 Determines Intestinal Identity through Repression of the Foregut Transcription Factor Irx5.

Kentaro Mori, Harumi Nakamura, Hisanori Kurooka, Hitoshi Miyachi, Kota Tamada, Manabu Sugai, Toru Takumi, Yoshifumi Yokota

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular and cellular biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.7field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Kentaro MoriDivision of Molecular Genetics, Department of Biochemistry and Bioinformative Sciences, School of Medicine, Faculty of Medical Sciences, University of Fukui, Eiheiji, Fukui, Japan kemori@u-fukui.ac.jp.ORCID 0000-0003-1498-9545
Harumi NakamuraDivision of Molecular Genetics, Department of Biochemistry and Bioinformative Sciences, School of Medicine, Faculty of Medical Sciences, University of Fukui, Eiheiji, Fukui, Japan.
Hisanori KurookaDivision of Molecular Genetics, Department of Biochemistry and Bioinformative Sciences, School of Medicine, Faculty of Medical Sciences, University of Fukui, Eiheiji, Fukui, Japan.
Hitoshi MiyachiExperimental Research Center for Infectious Diseases, Institute for Virus Research, Kyoto University, Shogoin-Kawahara, Sakyo-ku, Kyoto, Japan.
Kota TamadaRIKEN Brain Science Institute, Wako, Saitama, Japan.
Manabu SugaiDivision of Molecular Genetics, Department of Biochemistry and Bioinformative Sciences, School of Medicine, Faculty of Medical Sciences, University of Fukui, Eiheiji, Fukui, Japan.
Toru TakumiRIKEN Brain Science Institute, Wako, Saitama, Japan.
Yoshifumi YokotaDivision of Molecular Genetics, Department of Biochemistry and Bioinformative Sciences, School of Medicine, Faculty of Medical Sciences, University of Fukui, Eiheiji, Fukui, Japan.
University of Fukui · JPRIKEN Center for Brain Science · JPKyoto University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The cellular components and function of the gastrointestinal epithelium exhibit distinct characteristics depending on the region, e.g., stomach or intestine. How these region-specific epithelial characteristics are generated during development remains poorly understood. Here, we report on the involvement of the helix-loop-helix inhibitor Id2 in establishing the specific characteristics of the intestinal epithelium.

Indexed as

AnimalsCell DifferentiationGene Expression RegulationHomeodomain ProteinsInhibitor of Differentiation Protein 2Intestinal MucosaIntestinesIntestine, SmallMetaplasiaMiceMice, 129 StrainProtein DomainsStomachTranscription FactorsHomeodomain ProteinsIdb2 protein, mouseInhibitor of Differentiation Protein 2Irx3 protein, mouseIrx5 protein, mouseTranscription Factorscancercell differentiationcell fate specificationendodermgastric mucosaId2intestinal developmentintestinal epitheliumIrx transcription factortumorigenesis

Identifiers

PMID29463648
PMCPMC5902590
OpenAlexW2791516341

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.