Evidence map›Paper›PMID 29463537›Full record

ArticleAntimicrobial agents and chemotherapy2018

Impact of Oral Fidaxomicin Administration on the Intestinal Microbiota and Susceptibility to Clostridium difficile Colonization in Mice.

N J Ajami, J L Cope, M C Wong, J F Petrosino, L Chesnel

Open access · bronzeAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 1 pooled it
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 1 synthesis or guideline pooled it, 52 citations in OpenAlex.

  1. Microbiome changes associated with acute and chronic pancreatitis: A systematic review.Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] · 2021
    Pooled it
  2. Trial
  3. The gut as a central hub for multi-organ crosstalk in aging.Cellular and molecular life sciences : CMLS · 2026
    Review
  4. Article
  5. Article
  6. Multiple episodes of paediatricBMJ case reports · 2025
    Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Antimicrobial agents and chemotherapy · 2024
    Article
  14. Review
  15. Antibiotic perturbations to the gut microbiome.Nature reviews. Microbiology · 2023
    Review
  16. Review
  17. Article
  18. Article
  19. Fidaxomicin for the Treatment ofAntibiotics (Basel, Switzerland) · 2022
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

N J AjamiDiversigen, Inc., Houston, Texas, USA.
J L CopeDiversigen, Inc., Houston, Texas, USA.ORCID 0000-0003-4600-5600
M C WongAlkek Center for Metagenomics and Microbiome Research, Baylor College of Medicine, Houston, Texas, USA.
J F PetrosinoDiversigen, Inc., Houston, Texas, USA.
L ChesnelMerck Research Laboratories, Merck & Co., Inc., Kenilworth, New Jersey, USA laurent_chesnel@hotmail.com.
Baylor College of Medicine · USMerck & Co., Inc., Rahway, NJ, USA (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsAnti-Bacterial AgentsClostridioides difficileClostridium InfectionsCross InfectionDisease Models, AnimalFecesFemaleFidaxomicinGastrointestinal MicrobiomeMiceMice, Inbred C57BLRNA, Ribosomal, 16SVancomycinAnti-Bacterial AgentsFidaxomicinRNA, Ribosomal, 16SVancomycinClostridium difficilediarrheafidaxomicinrecurrencesvancomycin

Identifiers

PMID29463537
PMCPMC5923166
OpenAlexW2791617388

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.