Evidence map›Paper›PMID 29463526›Full record

Trial reportAntimicrobial agents and chemotherapy2018

Elevated Plasma Moxifloxacin Concentrations and

Marc Weiner, Jon Gelfond, Teresa L Johnson-Pais, Melissa Engle, Charles A Peloquin, John L Johnson, Erin E Sizemore, William R Mac Kenzie

Open access · bronzeAbstract readClinical Trial
In one paragraph

Trial report in Antimicrobial agents and chemotherapy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Observational
  6. Review
  7. Article
  8. Review
  9. Article
  10. Review
  11. Review
  12. Pharmacogenomics of Antibiotics.International journal of molecular sciences · 2020
    Review
  13. Review
  14. Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Marc WeinerUniversity of Texas Health Science Center, San Antonio, San Antonio, Texas, USA weiner@uthscsa.edu.
Jon GelfondUniversity of Texas Health Science Center, San Antonio, San Antonio, Texas, USA.
Teresa L Johnson-PaisUniversity of Texas Health Science Center, San Antonio, San Antonio, Texas, USA.
Melissa EngleUniversity of Texas Health Science Center, San Antonio, San Antonio, Texas, USA.
Charles A PeloquinCollege of Pharmacy, University of Florida, Gainesville, Florida, USA.
John L JohnsonCase Western Reserve University, Department of Medicine, Uganda-Case Western Reserve University Research Collaboration, Cleveland, Ohio, USA.
Erin E SizemoreDivision of Tuberculosis Elimination, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
William R Mac KenzieDivision of Tuberculosis Elimination, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
The University of Texas Health Science Center at San Antonio · USCenters for Disease Control and Prevention · USCase Western Reserve University · USUniversity of Florida · US

Funding

TISSUE CULTURE---COREP30CA054174 · NCI · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI Robin Jean Leach · 1991 to 2026
$59.1M
Institute for Integration of Medicine & Science: A Partnership to Improve HealthUL1TR001120 · NCATS · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI CLARK, ROBERT A, HARGREAVES, KENNETH M · 2013 to 2017
$16.5M
San Antonio OAIC - Research Education Component (REC)P30AG044271 · NIA · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI Adam Salmon · 2015 to 2026
$14.1M
NCATS NIH HHS UL1 TR001120NCI NIH HHS P30 CA054174NIA NIH HHS P30 AG044271
6 · The paper itself

Abstract

Moxifloxacin exhibits concentration-dependent prolongation of human QTc intervals and bactericidal activity against

Indexed as

AdultAfricaAgedAntitubercular AgentsArea Under CurveArrhythmias, CardiacFemaleHumansLiver-Specific Organic Anion Transporter 1MaleMiddle AgedMoxifloxacinMycobacterium tuberculosisPolymorphism, Single NucleotideTuberculosis, PulmonaryUnited StatesAntitubercular AgentsLiver-Specific Organic Anion Transporter 1MoxifloxacinSLCO1B1 protein, humanantibacterialfluoroquinolonespharmacogeneticspharmacokinetics

Identifiers

PMID29463526
PMCPMC5923103
OpenAlexW2793084722

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.