ArticlePublic health nutrition2018
Consumption of sugar-sweetened and artificially sweetened soft drinks and risk of obesity-related cancers.
Article in Public health nutrition, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers, 10 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
53 citing papers in PubMed, 10 syntheses or guidelines pooled it, 117 citations in OpenAlex.
- Dietary Glycemic Index, Glycemic Load, Sugar, and Fiber Intake in Association With Breast Cancer Risk: An Updated Meta-analysis.Nutrition reviews · 2025Pooled it
- Non-Sugar-Sweetened Beverages and Risk of Chronic Diseases: An Umbrella Review of Meta-analyses of Prospective Cohort Studies.Nutrition reviews · 2025Pooled it
- Association of sugar-sweetened beverages with the risk of colorectal cancer: a systematic review and meta-analysis.European journal of clinical nutrition · 2023Pooled it
- Association of soft drinks and 100% fruit juice consumption with risk of cancer: a systematic review and dose-response meta-analysis of prospective cohort studies.The international journal of behavioral nutrition and physical activity · 2023Pooled it
- Artificially Sweetened Beverage Consumption and Cancer Risk: A Comprehensive Dose-Response Meta-Analysis of Prospective Studies.Nutrients · 2022Pooled it
- Can Artificial Sweeteners Increase the Risk of Cancer Incidence and Mortality: Evidence from Prospective Studies.Nutrients · 2022Pooled it
- Pooled it
- Consumption of artificially sweetened soft drinks and risk of gastrointestinal cancer: a meta-analysis of observational studies.Public health nutrition · 2021Pooled it
- Intake of artificial sweeteners among adults is associated with reduced odds of gastrointestinal luminal cancers: a meta-analysis of cohort and case-control studies.Nutrition research (New York, N.Y.) · 2021Pooled it
- Consumption of Sweet Beverages and Cancer Risk. A Systematic Review and Meta-Analysis of Observational Studies.Nutrients · 2021Pooled it
- Urinary Concentrations of Non-Nutritive Sweeteners and Breast Cancer: A Case-Cohort Analysis of the Moli-sani Study.Nutrients · 2026Article
- Sugar sweetened and artificially sweetened beverages, fruit and vegetable juices and cancer risk: a World Cancer Research Fund International Global Cancer Update Programme (CUP Global) systematic literature review and meta-analysis.medRxiv : the preprint server for health sciences · 2026Article
- Serving Size Information and Portion Control Cues on Energy-Dense Nutrient-Poor Packaged Snacks in Australian Supermarkets: Current Practices and Opportunities.Foods (Basel, Switzerland) · 2026Article
- Incident cases and healthcare costs of non-communicable diseases attributable to industrialized and total sugar sweetened beverage intake in Mexico.BMC public health · 2025Article
- Circulating glycerate predicts resilience to fructose-induced hepatic steatosis.Cell metabolism · 2025Article
- Sweet beverages and the risk of colorectal cancer: the Norwegian Women and Cancer Study.BMC cancer · 2025Article
- The mediating roles of anthropo-metabolic biomarkers on the association between beverage consumption and breast cancer risk.Nutrition journal · 2025Article
- Association of sweetened beverage intake with incident risk of breast cancer: a prospective cohort study.Frontiers in nutrition · 2025Article
- Resistant starch reduces glycolysis by HK2 and suppresses high-fructose corn syrup-induced colon tumorigenesis.Journal of gastroenterology · 2024Article
- Chronic Use of Artificial Sweeteners: Pros and Cons.Nutrients · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo test the hypothesis that more frequent consumption of sugar-sweetened soft drinks would be associated with increased risk of obesity-related cancers. Associations for artificially sweetened soft drinks were assessed for comparison.
designProspective cohort study with cancers identified by linkage to cancer registries. At baseline, participants completed a 121-item FFQ including separate questions about the number of times in the past year they had consumed sugar-sweetened or artificially sweetened soft drinks. Anthropometric measurements, including waist circumference, were taken and questions about smoking, leisure-time physical activity and intake of alcoholic beverages were completed.
settingThe Melbourne Collaborative Cohort Study (MCCS) is a prospective cohort study which recruited 41 514 men and women aged 40-69 years between 1990 and 1994. A second wave of data collection occurred in 2003-2007. SUBJECTS: Data for 35 593 participants who developed 3283 incident obesity-related cancers were included in the main analysis.
resultsIncreasing frequency of consumption of both sugar-sweetened and artificially sweetened soft drinks was associated with greater waist circumference at baseline. For sugar-sweetened soft drinks, the hazard ratio (HR) for obesity-related cancers increased as frequency of consumption increased (HR for consumption >1/d v. 1/d v. <1/month=1·00; 95 % CI 0·79, 1·27; P-trend=0·61).
conclusionsOur results add to the justification to minimise intake of sugar-sweetened soft drinks.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.