ArticleBMC research notes2018
Molecular detection of colistin resistance genes (mcr-1 to mcr-5) in human vaginal swabs.
Article in BMC research notes, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
25 citing papers in PubMed.
- Molecular Characterization of Virulence Genes and Quinolone Resistance Determinants inAntibiotics (Basel, Switzerland) · 2026Article
- Understanding Recent Developments in Colistin Resistance: Mechanisms, Clinical Implications, and Future Perspectives.Antibiotics (Basel, Switzerland) · 2025Review
- Leveraging the microbiome to combat antibiotic resistant gynecological infections.npj antimicrobials and resistance · 2025Review
- Prevalence, characteristics, and plasmid dynamics ofFrontiers in microbiology · 2025Article
- A Review on Colistin Resistance: An Antibiotic of Last Resort.Microorganisms · 2024Review
- A multiplex TaqMan real-time PCR assays for the rapid detection of mobile colistin resistance (Frontiers in microbiology · 2024Article
- Antimicrobial resistance genes in a golden jackal (Canis aureus L. 1758) from Central Italy.Veterinary research communications · 2023Article
- Prevalence and epidemiological investigation of mgrB-dependent colistin resistance in extensively drug resistant Klebsiella pneumoniae in Iran.Scientific reports · 2023Article
- Colistin Resistance Genes in Broiler Chickens in Tunisia.Animals : an open access journal from MDPI · 2023Article
- Identification and characterization of plasmids carrying the mobile colistin resistance geneJAC-antimicrobial resistance · 2023Article
- The occurrence and molecular detection ofFrontiers in microbiology · 2023Article
- Prevalence of polymyxin resistance through the food chain, the global crisis.The Journal of antibiotics · 2022Review
- Occurrence ofFrontiers in microbiology · 2022Article
- Multiresistant Gram-Negative Pathogens—A Zoonotic Problem.Deutsches Arzteblatt international · 2021Review
- First Identification of a Patient with Prosthesis-Related Infection Caused by an MCR-1.1-Producing ST131Infection and drug resistance · 2021Article
- Colistin and its role in the Era of antibiotic resistance: an extended review (2000-2019).Emerging microbes & infections · 2020Review
- Emergence of plasmid-mediated mcr genes from Gram-negative bacteria at the human-animal interface.Gut pathogens · 2020Article
- Detection of Plasmid-Mediated Colistin ResistantAnimals : an open access journal from MDPI · 2020Article
- Plasmid mediated colistin resistantGut pathogens · 2020Article
- Emergence of mcr-1 conferred colistin resistance among bacterial isolates from urban sewage water in India.Environmental science and pollution research international · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
Abstract
objectiveColistin resistance has emerged worldwide and has been threatening the efficacy of one of the last-resort antimicrobials used for treatment of multidrug resistant Gram-negative bacteria. While five colistin resistance genes (mcr-1, mcr-2, mcr-3, mcr-4 and mcr-5) have been described, few data are available on the prevalence of mcr-genes other than mcr-1 in human samples.
resultsIn this study, the presence of five currently described colistin resistance genes (mcr 1-5) in vaginal swabs of women undergoing infertility evaluation was reported. Most samples were found to be positive for the mcr-4 (12.7%), followed by two for the mcr-2 (1.5%), two for the mcr-3 (1.5%), one for the mcr-1 (0.7%), and one for the mcr-5 (0.7%). Phylogenetic comparison demonstrated identical (mcr-1, mcr-2, mcr-3, mcr-5) or similar (mcr-4) nucleotide sequences of human samples and those of animal origins from the same city, suggesting the potential transmission of mcr genes from animals to humans. This is the first detection of mcr-2, mcr-4 and mcr-5 genes in human samples, and warrants further research to determine the spread of the mcr genes and elucidate the full epidemiology of colistin resistance genes in humans.
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