Evidence map›Paper›PMID 29462879›Full record

ArticleViruses2018

Chondrocytes Contribute to Alphaviral Disease Pathogenesis as a Source of Virus Replication and Soluble Factor Production.

Elisa X Y Lim, Aroon Supramaniam, Hayman Lui, Peta Coles, Wai Suet Lee, Xiang Liu, Penny A Rudd, Lara J Herrero

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Viruses, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.4field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
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  11. Prophylactic Antiheparanase Activity by PG545 Is AntiviralAntimicrobial agents and chemotherapy · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Elisa X Y LimInstitute for Glycomics, Griffith University, Gold Coast Campus, Southport, QLD 4215, Australia. elisa.lim@griffithuni.edu.au.
Aroon SupramaniamInstitute for Glycomics, Griffith University, Gold Coast Campus, Southport, QLD 4215, Australia. aroon.supramaniam@griffithuni.edu.au.
Hayman LuiInstitute for Glycomics, Griffith University, Gold Coast Campus, Southport, QLD 4215, Australia. hayman.lui@griffithuni.edu.au.
Peta ColesInstitute for Glycomics, Griffith University, Gold Coast Campus, Southport, QLD 4215, Australia. peta.coles@griffithuni.edu.au.
Wai Suet LeeInstitute for Glycomics, Griffith University, Gold Coast Campus, Southport, QLD 4215, Australia. waisuet.lee@griffithuni.edu.au.
Xiang LiuInstitute for Glycomics, Griffith University, Gold Coast Campus, Southport, QLD 4215, Australia. xiang.liu@griffithuni.edu.au.
Penny A RuddInstitute for Glycomics, Griffith University, Gold Coast Campus, Southport, QLD 4215, Australia. p.rudd@griffith.edu.au.
Lara J HerreroInstitute for Glycomics, Griffith University, Gold Coast Campus, Southport, QLD 4215, Australia. l.herrero@griffith.edu.au.ORCID 0000-0002-5661-9828
Griffith University · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Arthritogenic alphavirus infections often result in debilitating musculoskeletal disorders that affect the joints, muscle, and bone. In order to evaluate the infection profile of primary human skeletal muscle and chondrocyte cells to Ross River virus (RRV) in vitro, cells were infected at a multiplicity of infection (MOI) of 1 over a period of two days. Viral titers were determined by plaque assay and cytokine expression by Bio-Plex

Indexed as

Virus ReplicationAlphavirusAlphavirus InfectionsAnimalsBiomarkersCells, CulturedChondrocytesCytokinesGene Expression ProfilingHumansInflammation MediatorsMiceMuscle CellsTranscriptomeBiomarkersCytokinesInflammation Mediatorscartilage degradationinflammatory diseaseviral arthritis

Identifiers

PMID29462879
PMCPMC5850393
OpenAlexW2791641993

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.