Evidence map›Paper›PMID 29462871›Full record

ReviewMolecules (Basel, Switzerland)2018

Taming the Notch Transcriptional Regulator for Cancer Therapy.

Luca Tamagnone, Serena Zacchigna, Michael Rehman

Abstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Review
  11. Review
  12. Article
  13. Review
  14. Review
  15. Review
  16. Targeting Notch in oncology: the path forward.Nature reviews. Drug discovery · 2021
    Review
  17. Review
  18. Article
  19. Article
  20. A Novel Flow Cytometric Assay to Identify Inhibitors of RBPJ-DNA Interactions.SLAS discovery : advancing life sciences R & D · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Luca TamagnoneLaboratory of Cancer Cell Biology, Candiolo Cancer Institute-FPO, IRCCS, Str. Prov. 142, 10060 Candiolo, TO, Italy. luca.tamagnone@ircc.it.ORCID 0000-0002-2884-7946
Serena ZacchignaDepartment of Medical, Surgical and Health Sciences, University of Trieste, 34127 Trieste, Italy. zacchign@icgeb.org.
Michael RehmanDepartment of Medical, Surgical and Health Sciences, University of Trieste, 34127 Trieste, Italy. rehman@icgeb.org.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Cell DifferentiationCell ProliferationGene Expression Regulation, NeoplasticHumansNeoplasmsReceptors, NotchSignal TransductionSmall Molecule LibrariesReceptors, NotchSmall Molecule Librariesblocking antibodyclinical trialscombination therapygamma secretase inhibitorsNotch transcription complex

Identifiers

PMID29462871
PMCPMC6017063

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.