Evidence map›Paper›PMID 29462793›Full record

ArticleThe Journal of biological chemistry2018

The human platelet antigen-1b (Pro

Giulia Pagani, Joana P V Pereira, Volker R Stoldt, Andreas Beck, Rüdiger E Scharf, Holger Gohlke

Abstract read
In one paragraph

Article in The Journal of biological chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Analysis of Integrin αInternational journal of molecular sciences · 2022
    Article
  3. Article
  4. Article
  5. Frequency and Association of Polymorphisms in F2, F7, and PROS1 Coagulation Genes with Disease Severity in Coronavirus Disease 2019.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Giulia PaganiInstitute for Pharmaceutical and Medicinal Chemistry, 40225 Düsseldorf, Germany.
Joana P V PereiraDivision of Experimental and Clinical Hemostasis, Hemotherapy and Transfusion Medicine, Institute of Transplantation Diagnostics and Cell Therapeutics, Heinrich Heine University Medical Center, 40225 Düsseldorf, Germany.
Volker R StoldtDivision of Experimental and Clinical Hemostasis, Hemotherapy and Transfusion Medicine, Institute of Transplantation Diagnostics and Cell Therapeutics, Heinrich Heine University Medical Center, 40225 Düsseldorf, Germany.
Andreas BeckInstitute of Informatics, 40225 Düsseldorf, Germany.
Rüdiger E ScharfDivision of Experimental and Clinical Hemostasis, Hemotherapy and Transfusion Medicine, Institute of Transplantation Diagnostics and Cell Therapeutics, Heinrich Heine University Medical Center, 40225 Düsseldorf, Germany; Biological Medical Research Center, Heinrich Heine University Düsseldorf, 40225 Düsseldorf, Germany.
Holger GohlkeInstitute for Pharmaceutical and Medicinal Chemistry, 40225 Düsseldorf, Germany; John von Neumann Institute for Computing (NIC), Jülich Supercomputing Centre (JSC), and Institute for Complex Systems-Structural Biochemistry (ICS 6), Forschungszentrum Jülich GmbH, 52425 Jülich, Germany. Electronic address: gohlke@uni-duesseldorf.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Integrins are heterodimeric cell-adhesion receptors comprising α and β subunits that transmit signals allosterically in both directions across the membrane by binding to intra- and extracellular components. The human platelet antigen-1 (HPA-1) polymorphism in α

Indexed as

Platelet AggregationSignal TransductionAllosteric RegulationAntigens, Human PlateletBlood PlateletsHEK293 CellsHumansIntegrin beta3Platelet Glycoprotein GPIIb-IIIa ComplexThrombosisAntigens, Human Platelethuman platelet antigen 1bIntegrin beta3ITGB3 protein, humanPlatelet Glycoprotein GPIIb-IIIa Complexactivationconformational changefluorescence resonance energy transferFRETintegrinmolecular dynamicsplateletpolymorphismstructural dynamicsthrombus

Identifiers

PMID29462793
PMCPMC5880125

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.