Evidence map›Paper›PMID 29462786›Full record

ArticleThe Journal of biological chemistry2018

Distinct properties underlie flavin-based electron bifurcation in a novel electron transfer flavoprotein FixAB from

H Diessel Duan, Carolyn E Lubner, Monika Tokmina-Lukaszewska, George H Gauss, Brian Bothner, Paul W King, John W Peters, Anne-Frances Miller

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 31 citations in OpenAlex.

  1. Biophysical journal · 2026
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  14. One-megadalton metalloenzyme complex inProceedings of the National Academy of Sciences of the United States of America · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

H Diessel DuanDepartment of Chemistry, University of Kentucky, Lexington, Kentucky 40506.
Carolyn E LubnerNational Renewable Energy Laboratory, Golden, Colorado 80401.
Monika Tokmina-LukaszewskaDepartment of Chemistry and Biochemistry, Montana State University, Bozeman, Montana 59717.
George H GaussDepartment of Chemistry and Biochemistry, Montana State University, Bozeman, Montana 59717.
Brian BothnerDepartment of Chemistry and Biochemistry, Montana State University, Bozeman, Montana 59717.
Paul W KingNational Renewable Energy Laboratory, Golden, Colorado 80401.
John W PetersInstitute of Biological Chemistry, Washington State University, Pullman, Washington 99163.
Anne-Frances MillerDepartment of Chemistry, University of Kentucky, Lexington, Kentucky 40506. Electronic address: afmill3r2@gmail.com.
Montana State University · USNational Renewable Energy Laboratory · USUniversity of Kentucky · USWashington State University · US

Funding

Research Core (Developmental Research Project Program)P20GM103474 · NIGMS · MONTANA STATE UNIVERSITY - BOZEMAN · PI Jeffrey Good · 2012 to 2026
$60.0M
NIGMS NIH HHS P20 GM103474
6 · The paper itself

Abstract

A newly recognized third fundamental mechanism of energy conservation in biology, electron bifurcation, uses free energy from exergonic redox reactions to drive endergonic redox reactions. Flavin-based electron bifurcation furnishes low-potential electrons to demanding chemical reactions, such as reduction of dinitrogen to ammonia. We employed the heterodimeric flavoenzyme FixAB from the diazotrophic bacterium

Indexed as

Adenosine MonophosphateBacterial ProteinsElectron-Transferring FlavoproteinsFlavin-Adenine DinucleotideRhodopseudomonasThermodynamicsAdenosine MonophosphateBacterial ProteinsElectron-Transferring FlavoproteinsFlavin-Adenine Dinucleotidecircular dichroism (CD)Electron bifurcationelectron transferelectron transfer flavoproteinETFFixABflavinflavoproteinnitrogenaseReduction midpoint potential

Identifiers

PMID29462786
PMCPMC5880144
OpenAlexW2787635308

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.