ArticlePloS one2018
Association between somatic symptom burden and health-related quality of life in people with chronic low back pain.
Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
25 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Measurement Properties of the Patient Health Questionnaire-15 and Somatic Symptom Scale-8: A Systematic Review and Meta-Analysis.JAMA network open · 2024Pooled it
- Distribution and prevalence of musculoskeletal pain co-occurring with persistent low back pain: a systematic review.BMC musculoskeletal disorders · 2021Pooled it
- Impact of Vojta therapy combined with standard care on psychometric and functional parameters in patients with chronic lower back pain: a randomized controlled trial.Journal of medicine and life · 2024Trial
- The Role of Behavioral and Psychological Interventions in Chronic Ocular Pain.Current pain and headache reports · 2026Review
- Psychometric Assessment of Screening Measures for Depression, Anxiety, Somatization, and Life Satisfaction in Honduran University Students.Behavioral sciences (Basel, Switzerland) · 2025Article
- Psychometric Evaluation of Indonesian Version of the Somatic Symptom Scale-8 (ISSS-8).Journal of caring sciences · 2025Review
- Psychopathological Symptomatology and Sleep Quality in Chronic Primary Musculoskeletal Pain: A Comparison with Healthy Controls.Healthcare (Basel, Switzerland) · 2025Article
- Chronic disease clusters and health-related quality of life among individuals with musculoskeletal pain: a Northern Finland Birth Cohort 1966 study.Family practice · 2025Article
- Predictors for Poor Outcomes at Six Months on Pain, Disability, Psychological and Health Status in Greek Patients with Chronic Low Back Pain After Receiving Physiotherapy: A Prospective Cohort Study.Clinics and practice · 2025Article
- The association between childhood sexual abuse and somatic symptoms at midlife: The roles of depression and intimate partner relationship quality.Journal of family violence · 2024Article
- Is the PHQ-2 a Good Measure to Inform Providers About Patient Well-Being and Functioning? Data From the Veterans Health and Life Survey.Medical care · 2024Article
- Systematic Review of the Psychopathological Symptomatology and Neuropsychological Disorders of Chronic Primary Musculoskeletal Pain.Healthcare (Basel, Switzerland) · 2024Review
- Chronic pain-mental health comorbidity and excess prevalence of health risk behaviours: a cross-sectional study.Primary health care research & development · 2024Article
- The burden of persistent symptom diagnoses in primary care patients: a cross-sectional study.Scandinavian journal of primary health care · 2024Article
- Geographical variation in high-impact chronic pain and psychological associations at the regional level: a multilevel analysis of a large-scale internet-based cross-sectional survey.Frontiers in public health · 2024Article
- Psychological flexibility and global health in young adults with and without a self-reported functional somatic syndrome: a preliminary investigation.Psychology, health & medicine · 2023Article
- Association between Eating Patterns and Quality of Life in Patients with Familial Hypercholesterolemia.Nutrients · 2023Article
- The relationship between the Keele STarT back screening tool, the short form of central sensitivity inventory and health-related quality of life in patients with low back pain.The Journal of manual & manipulative therapy · 2022Article
- Determinants of quality of life in individuals with chronic low back pain: a systematic review.Health psychology and behavioral medicine · 2022Review
- Role of psychological distress screening in predicting the outcomes of epidural steroid injection in chronic low back pain.Journal of clinical orthopaedics and trauma · 2021Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Depression is a relevant risk factor for low back pain and is associated with the outcomes of low back pain. Depression also often overlaps with somatisation. As previous studies have suggested that somatisation or a higher somatic symptom burden has a role in the outcomes of low back pain, the aim of the present cross-sectional study was to examine whether somatic symptom burden was associated with health-related quality of life in individuals with chronic low back pain independent of depression. We analyzed internet survey data on physical and mental health in Japanese adults aged 20-64 years with chronic low back pain (n = 3,100). Health-related quality of life was assessed using the EuroQol five dimensions (EQ-5D) questionnaire. Somatic symptom burden and depression were assessed using the Somatic Symptom Scale-8 (SSS-8) and the Patient Health Questionnaire-2 (PHQ-2), respectively. SSS-8 score was categorized as no to minimal (0-3), low (4-7), medium (8-11), high (12-15), and very high (16-32). The association between SSS-8 and EQ-5D was examined using linear regression models, adjusting for depression and other covariates, including age, sex, BMI, smoking, marital status, education, exercise, employment, and the number of comorbid diseases. A higher somatic symptom burden was significantly associated with a lower health-related quality of life independent of depression and the number of comorbid diseases (regression coefficient = 0.040 for SSS-8 high vs. very high and 0.218 for non to minimal vs. very high, p trend <0.0001). In conclusion, somatic symptom burden might be important for the health-related quality of life of individuals with chronic low back pain.
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