Evidence map›Paper›PMID 29462107›Full record

ArticleThe Pediatric infectious disease journal2018

Tracheal Microbiota in Patients With a Tracheostomy Before, During and After an Acute Respiratory Infection.

Marcos Pérez-Losada, Robert J Graham, Madeline Coquillette, Amenah Jafarey, Eduardo Castro-Nallar, Manuel Aira, Claire Hoptay, Robert J Freishtat, Jonathan M Mansbach

Registry-linked trialAbstract read
In one paragraph

Article in The Pediatric infectious disease journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06201130 (Airway Microbiome Changes After Artificial Airway Exchange in Critically-ill Pediatric Patients.), which is not on this map. Cited by 11 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06201130 unknown statusnot on this mapstarted 2023, after this paper: background citation

Airway Microbiome Changes After Artificial Airway Exchange in Critically-ill Pediatric Patients.

TypeobservationalSponsorNorthwell HealthRan2023 to 2025Enrolled50ConditionsTracheostomy, Endotracheal Tube, Ventilator Associated Pneumonia, TracheitisArmsSuctioning of artificial airway
3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Guideline
  2. Pooled it
  3. Article
  4. Review
  5. Article
  6. The Human Microbiome-A Physiologic Perspective.Comprehensive Physiology · 2024
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Marcos Pérez-LosadaFrom the Computational Biology Institute, Milken Institute School of Public Health, George Washington University, Ashburn, VA.
Robert J GrahamDivision of Critical Care Medicine, Department of Anesthesiology, Perioperative, and Pain Medicine.
Madeline CoquilletteDepartment of Medicine, Boston Children's Hospital, Harvard Medical School, Boston, MA.
Amenah JafareyChildren's National Health System, Washington, DC.
Eduardo Castro-NallarCenter for Bioinformatics and Integrative Biology, Facultad de Ciencias Biológicas, Universidad Andrés Bello, Santiago, Chile.
Manuel AiraDepartamento de Ecoloxía e Bioloxía Animal, Universidade de Vigo, Vigo, Spain.
Claire HoptayChildren's National Health System, Washington, DC.
Robert J FreishtatChildren's National Health System, Washington, DC.
Jonathan M MansbachDepartment of Medicine, Boston Children's Hospital, Harvard Medical School, Boston, MA.

Funding

Clinical and Translational Science Institute at Childrens NationalUL1TR001876 · NCATS · CHILDREN'S RESEARCH INSTITUTE · PI BELL, MICHAEL J · 2016 to 2021
$25.6M
Clinical and Translational Science Institute at Childrens National-Mentored Career Development CoreKL2TR001877 · NCATS · CHILDREN'S RESEARCH INSTITUTE · PI LUBAN, NAOMI L · 2016 to 2020
$2.0M
K12 Career Development Program: Omics of Pediatric Lung Diseases in DCK12HL119994 · NHLBI · CHILDREN'S RESEARCH INSTITUTE · PI FREISHTAT, ROBERT J · 2013 to 2017
$1.3M
NCATS NIH HHS KL2 TR001877NCATS NIH HHS UL1 TR001876NHLBI NIH HHS K12 HL119994
6 · The paper itself

Abstract

Examining tracheal microbiota before, during and after acute respiratory infection in patients with a tracheostomy demonstrated large baseline intrapatient microbiota variability and a significant bloom of Haemophilus and Moraxella on day 1 of acute respiratory infection symptoms. The tracheal microbiota community composition changed significantly from baseline to 1 month after acute respiratory infection.

Indexed as

MicrobiotaTracheostomyAcute DiseaseAdolescentBacteriaChildChild, PreschoolCohort StudiesFemaleHaemophilus influenzaeHigh-Throughput Nucleotide SequencingHumansMaleMoraxellaRespiratory Tract InfectionsRNA, Ribosomal, 16SRNA, Ribosomal, 16S

Identifiers

PMID29462107
PMCPMC6097614

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.