Evidence map›Paper›PMID 29460736›Full record

ArticleEmerging infectious diseases2018

Epidemiology and Molecular Identification and Characterization of Mycoplasma pneumoniae, South Africa, 2012-2015.

Maimuna Carrim, Nicole Wolter, Alvaro J Benitez, Stefano Tempia, Mignon du Plessis, Sibongile Walaza, Fahima Moosa, Maureen H Diaz, Bernard J Wolff, Florette K Treurnicht and 6 more

Abstract readHistorical Article
In one paragraph

Article in Emerging infectious diseases, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Trial
  2. Genomic surveillance of the pneumonia outbreak caused byFrontiers in cellular and infection microbiology · 2026
    Article
  3. Article
  4. P1 adhesin genotype characteristics ofFrontiers in cellular and infection microbiology · 2025
    Article
  5. Article
  6. Detection ofWellcome open research · 2023
    Article
  7. Article
  8. Article
  9. Laboratory analysis of positive rate ofTranslational pediatrics · 2022
    Article
  10. Article
  11. Article
  12. Article
  13. Characteristics and Outcome of SevereCritical care explorations · 2021
    Article
  14. Article
  15. Article
  16. Article
  17. Etiology of Pulmonary Infections in Human Immunodeficiency Virus-infected Inpatients Using Sputum Multiplex Real-time Polymerase Chain Reaction.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2020
    Article
  18. Article
  19. Community-acquired pneumonia: The need to broaden our diagnostic armamentarium.African journal of thoracic and critical care medicine · 2020
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Maimuna Carrim
Nicole Wolter
Alvaro J Benitez
Stefano Tempia
Mignon du Plessis
Sibongile Walaza
Fahima Moosa
Maureen H Diaz
Bernard J Wolff
Florette K Treurnicht
Orienka Hellferscee
Halima Dawood
Ebrahim Variava
Cheryl Cohen
Jonas M Winchell
Anne von Gottberg

Funding

Research on the Epidemiology,Prevention,Vaccine Effectiveness and Treatment of Influenza and Other Respiratory Viruses in South Africa.09U01IP001048 · IP · NATIONAL HEALTH LABORATORY SERVICE · PI COHEN, CHERYL · 2016 to 2020
$19.9M
South African Preparedness for Rapid Detection of Highly Pathogenic Avian InfluenU51IP000155 · IP · NATIONAL INST FOR COMMUNICABLE DISEASES · PI VENTER, MARIETJIE · 2007 to 2010
$6.7M
NCIRD CDC HHS U01 IP001048NCIRD CDC HHS U51 IP000155
6 · The paper itself

Abstract

During 2012-2015, we tested respiratory specimens from patients with severe respiratory illness (SRI), patients with influenza-like illness (ILI), and controls in South Africa by real-time PCR for Mycoplasma pneumoniae, followed by culture and molecular characterization of positive samples. M. pneumoniae prevalence was 1.6% among SRI patients, 0.7% among ILI patients, and 0.2% among controls (p<0.001). Age <5 years (adjusted odd ratio 7.1; 95% CI 1.7-28.7) and HIV infection (adjusted odds ratio 23.8; 95% CI 4.1-138.2) among M. pneumonia-positive persons were associated with severe disease. The detection rate attributable to illness was 93.9% (95% CI 74.4%-98.5%) in SRI patients and 80.7% (95% CI 16.7%-95.6%) in ILI patients. The hospitalization rate was 28 cases/100,000 population. We observed the macrolide-susceptible M. pneumoniae genotype in all cases and found P1 types 1, 2, and a type 2 variant with multilocus variable number tandem repeat types 3/6/6/2, 3/5/6/2, and 4/5/7/2.

Indexed as

Mycoplasma pneumoniaeAdolescentAdultAgedAged, 80 and overChildChild, PreschoolCommunity-Acquired InfectionsFemaleGenotypeHistory, 21st CenturyHospitalizationHumansInfantMaleMiddle Agedantimicrobial resistancebacteriabacterial infectioncommunity-acquired pneumoniainfluenza-like illnessmacrolide susceptibilitymolecular characterizationMycoplasma pneumoniaereal-time PCRrespiratory infectionssevere respiratory illnessSouth Africa

Identifiers

PMID29460736
PMCPMC5823326

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.