SynthesisDiabetic medicine : a journal of the British Diabetic Association2018
Investigating the longitudinal association between diabetes and anxiety: a systematic review and meta-analysis.
Synthesis in Diabetic medicine : a journal of the British Diabetic Association, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
60 citing papers in PubMed, 2 syntheses or guidelines pooled it, 126 citations in OpenAlex.
- Art Therapy Alleviates the Levels of Depression and Blood Glucose in Diabetic Patients: A Systematic Review and Meta-Analysis.Frontiers in psychology · 2021Pooled it
- Investigating the longitudinal association between diabetes and anxiety: a systematic review and meta-analysis.Diabetic medicine : a journal of the British Diabetic Association · 2018Pooled it
- Effects of Tai Chi and Qigong intervention on anxiety and stress in diabetic and hypertensive Brazilian patients: a randomized controlled trial.Einstein (Sao Paulo, Brazil) · 2025Trial
- Trial
- Sociodemographic Characteristics and Dietary Habits Associated with Generalized Anxiety Disorder Symptoms in Adults Living in the Kingdom of Saudi Arabia: A Large Cross-Sectional Study.Healthcare (Basel, Switzerland) · 2026Article
- Clarifying the Association Between Food Insecurity and Chronic Disease: Why Methods Matter.Current nutrition reports · 2026Review
- Elevated cortisol in patients with type 2 diabetes mellitus and comorbid depressive symptoms is associated with poor glycemic control and reduced insulin levels.Discover mental health · 2026Article
- Review
- Prevalence and associated factors of depression and anxiety in Saudi adults with type 1 diabetes: a cross-sectional study.Scientific reports · 2026Article
- Healthcare utilisation, diagnosed depression and anxiety among US adults with diagnosed diabetes and pre-diabetes, 2021-2023: a national cross-sectional study.BMJ public health · 2026Article
- Philippine Clinical Practice Guidelines for Periodic Health Examination: Screening for Mental Health and Addiction.Acta medica Philippina · 2026Article
- Lifestyle Interventions for Treatment and Remission of Type 2 Diabetes and Prediabetes in Adults: A Clinical Practice Guideline From the American College of Lifestyle Medicine.American journal of lifestyle medicine · 2025Article
- Neuronal CCL2 responds to hyperglycaemia and contributes to anxiety disorders in the context of diabetes.Nature metabolism · 2025Article
- The role of glycemic control and symptoms and symptom clusters in breast cancer survivors with type 2 diabetes.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Article
- Combined symptoms of diabetes distress, depression, and anxiety and their association with glycemic control in primary care patients with type 2 diabetes in Egypt.Diabetology international · 2025Article
- Socioeconomic disparities in the prevalence of depression and anxiety, and their associations with diabetes in rural southwest China.BMC public health · 2025Article
- Workload Is Associated with Anxiety and Insomnia Symptoms in an Italian Nationally Representative Sample of Public Health Medical Residents: The PHRASI Cross-Sectional Study.Healthcare (Basel, Switzerland) · 2024Article
- Anxiety and Depression Among Patients with Diabetes in Saudi Arabia and Egypt.Healthcare (Basel, Switzerland) · 2024Article
- Depression, Anxiety, and Health-Related Quality of Life in Adults with Type 2 Diabetes.Journal of clinical medicine · 2024Article
- Association Between Family History of Diabetes, Irrational Beliefs, and Health Anxiety with 10-Year Risk of Type 2 Diabetes Mellitus: the ATTICA Epidemiological Study (2002-2012).International journal of behavioral medicine · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimPrevious research has indicated an association between diabetes and anxiety. However, no synthesis has determined the direction of this association. The aim of this study was to determine the longitudinal relationship between anxiety and diabetes.
methodsWe searched seven databases for studies examining the longitudinal relationship between anxiety and diabetes. Two independent reviewers screened studies from a population aged 16 or older that examined either anxiety as a risk factor for incident diabetes or diabetes as a risk factor for incident anxiety. Studies that met eligibility criteria were put forward for data extraction and meta-analysis.
resultsIn total 14 studies (n = 1 760 800) that examined anxiety as a risk factor for incident diabetes and two (n = 88 109) that examined diabetes as a risk factor for incident anxiety were eligible for inclusion in the review. Only studies examining anxiety as a risk factor for incident diabetes were put forward for the meta-analysis. The least adjusted (unadjusted or adjusted for age only) estimate indicated a significant association between baseline anxiety with incident diabetes (odds ratio 1.47, 1.23-1.75). Furthermore, most-adjusted analyses indicated a significant association between baseline anxiety and incident diabetes. Included studies that examined diabetes to incident anxiety found no association.
conclusionsThere was an association between baseline anxiety and incident diabetes. The results also indicate the need for more research to examine the direction of association from diabetes to incident anxiety. This work adds to the growing body of evidence that poor mental health increases the risk of developing diabetes.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.