Evidence map›Paper›PMID 29460362›Full record

ArticleJournal of research on adolescence : the official journal of the Society for Research on Adolescence2018

Prefrontal Cortical Response to Negative Social Words Links Social Risk to Depressive Symptoms in Adolescence.

Kyung Hwa Lee, Caroline W Oppenheimer, Greg J Siegle, Cecile D Ladouceur, Grace E Lee, Jennifer S Silk, Ronald E Dahl

Erratum issuedAbstract readComparative Study
In one paragraph

Article in Journal of research on adolescence : the official journal of the Society for Research on Adolescence, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Prefrontal cortex and depression.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2022
    Review
  3. Adolescent Brain Development: Implications for Understanding Risk and Resilience Processes Through Neuroimaging Research.Journal of research on adolescence : the official journal of the Society for Research on Adolescence · 2018
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Kyung Hwa LeeUniversity of Pittsburgh.
Caroline W OppenheimerUniversity of Pittsburgh.
Greg J SiegleUniversity of Pittsburgh.
Cecile D LadouceurUniversity of Pittsburgh.
Grace E LeeUniversity of Pittsburgh.
Jennifer S SilkUniversity of Pittsburgh.
Ronald E DahlUniversity of California, Berkeley.

Funding

Emotion Regulation in Adolescence: A Social Affective Neuroscience ApproachR21DA024144 · NIDA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI DAHL, RONALD E., SILK, JENNIFER S · 2007 to 2010
$1.2M
Predicting Suicide Risk in Sexual Minority and Nonminority Youth: Associations Among Neural Sensitivity to Social Rejection, Peer Rejection, and SuicidalityK01MH109850 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI OPPENHEIMER, CAROLINE · 2016 to 2020
$794k
NIDA NIH HHS R21 DA024144NIMH NIH HHS K01 MH109850
6 · The paper itself

Abstract

Research suggests that altered emotion processing may be one important pathway linking social risk factors and depressive symptoms. We examined the extent to which neural response to negatively valenced social information might help to account for the relationship between social risk and depressive symptoms in youth. Forty-nine youth were scanned while identifying the emotional valence of words that connoted social status. They also completed questionnaires assessing self-reported social risk factors and depressive symptoms. Mediation analysis revealed that reduced dorsolateral prefrontal cortex activity in response to negative social status words explained the positive association between social risk and depressive symptoms. These findings suggest that social risk factors present during adolescence may contribute to depressive symptoms by influencing the neural substrates of emotion processing.

Indexed as

AdolescentBrain MappingChildEmotionsFemaleHumansMagnetic Resonance ImagingMajor Depressive DisorderMaleNegotiatingPrefrontal CortexRisk FactorsSelective Serotonin Reuptake InhibitorsSelf ReportSocial ChangeSelective Serotonin Reuptake Inhibitors

Identifiers

PMID29460362
PMCPMC5926184

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.