Evidence map›Paper›PMID 29460101›Full record

ArticleOsteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA2018

Pulse-echo ultrasound method for detection of post-menopausal women with osteoporotic BMD.

J P Karjalainen, O Riekkinen, H Kröger

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Fragility fracture discriminative ability of radius quantitative ultrasound: a systematic review and meta-analysis.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2021
    Pooled it
  2. Trial
  3. Trial
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Bone Biomarkers Based on Magnetic Resonance Imaging.Seminars in musculoskeletal radiology · 2024
    Review
  10. Article
  11. Article
  12. Clinical Devices for Bone Assessment.Advances in experimental medicine and biology · 2022
    Review
  13. Article
  14. Article
  15. Application of a Neural Network Classifier to Radiofrequency-Based Osteopenia/Osteoporosis Screening.IEEE journal of translational engineering in health and medicine · 2021
    Article
  16. Review
  17. Associations between radius low-frequency axial ultrasound velocity and bone fragility in elderly men and women.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2019
    Article
  18. Cost-effectiveness of pulse-echo ultrasonometry in osteoporosis management.ClinicoEconomics and outcomes research : CEOR · 2018
    Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

J P KarjalainenBone Index Finland Ltd., Kuopio, Finland. janne.p.karjalainen@iki.fi.
O RiekkinenBone Index Finland Ltd., Kuopio, Finland.
H KrögerDepartment of Orthopaedics, Traumatology and Hand Surgery, Kuopio University Hospital, Kuopio, Finland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We lack effective diagnostics of osteoporosis at the primary health care level. An ultrasound device was used to identify subjects in the osteoporotic range as defined by DXA. A case finding strategy combining ultrasound results with DXA measurements for patients with intermediate ultrasound results is presented.

introductionWe lack effective screening and diagnostics of osteoporosis at primary health care. In this study, a pulse-echo ultrasound (US) method is investigated for osteoporosis screening.

methodsA total of 1091 Caucasian women (aged 50-80 years) were recruited for the study and measured with US in the tibia and radius. This method measures cortical thickness and provides an estimate of bone mineral density (BMD) and density index (DI). BMD assessment of the hip was available for 988 women. A total of 888 women had one or more risk factors for osteoporosis (OP

resultsIn the OP

conclusionsThe study data demonstrate that a strategy of combining ultrasound measurement with added DXA measurements in cases with intermediate ultrasound results (about 30%) can be useful for identifying subjects at risk for a low bone mineral density in the osteoporotic range.

Indexed as

Absorptiometry, PhotonAgedAged, 80 and overBone DensityFemaleHumansMass ScreeningMiddle AgedOsteoporosis, PostmenopausalOsteoporotic FracturesPredictive Value of TestsPrimary Health CareRadiusReproducibility of ResultsRisk FactorsSensitivity and SpecificityBoneDXAOsteoporosisScreeningUltrasound

Identifiers

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.