ArticleEuropean radiology2018
Experimental feasibility of spectral photon-counting computed tomography with two contrast agents for the detection of endoleaks following endovascular aortic repair.
Article in European radiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers.
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Who cites it
51 citing papers in PubMed, 93 citations in OpenAlex.
- A scoping review of photon-counting detector computed tomography in cardiovascular imaging.Diagnostic and interventional radiology (Ankara, Turkey) · 2026Article
- K-Edge imaging using a clinical dual-source photon-counting CT system.Journal of applied clinical medical physics · 2026Article
- The Applications of Spectral CT in Interventional Radiology: Innovations in Diagnosis and Intra-procedural Guidance.Cardiovascular and interventional radiology · 2026Review
- CT material decomposition with contrast agents: Single or multiple spectral photon-counting CT scans? A simulation study.Medical physics · 2025Article
- Can the Novel Photon-Counting CT Scan Accurately Predict Aortic Wall Thickness? Preliminary Results.Bioengineering (Basel, Switzerland) · 2025Article
- Technical principles, benefits, challenges, and applications of photon counting computed tomography in coronary imaging: a narrative review.Cardiovascular diagnosis and therapy · 2024Review
- Visual and Quantitative Evaluation of Low-Concentration Bismuth in Dual-Contrast Imaging of Iodine and Bismuth Using Clinical Photon-Counting CT.Sensors (Basel, Switzerland) · 2024Article
- Improvement of Neurovascular Imaging Using Ultra-High-Resolution Computed Tomography Angiography.Clinical neuroradiology · 2024Article
- Unenhanced computed tomography radiomics help detect endoleaks after endovascular repair of abdominal aortic aneurysm.European radiology · 2024Article
- Advantages of Photon-Counting Detector CT in Aortic Imaging.Tomography (Ann Arbor, Mich.) · 2023Review
- Dual-Source Photon-Counting Computed Tomography-Part III: Clinical Overview of Vascular Applications beyond Cardiac and Neuro Imaging.Journal of clinical medicine · 2023Review
- Dual-Source Photon-Counting Computed Tomography-Part I: Clinical Overview of Cardiac CT and Coronary CT Angiography Applications.Journal of clinical medicine · 2023Review
- An introduction to photon-counting detector CT (PCD CT) for radiologists.Japanese journal of radiology · 2023Review
- Three-dimensional printing of patient-specific computed tomography lung phantoms: a reader study.PNAS nexus · 2023Article
- Photon-Counting Computed Tomography (PCCT): Technical Background and Cardio-Vascular Applications.Diagnostics (Basel, Switzerland) · 2023Review
- Article
- First-generation clinical dual-source photon-counting CT: ultra-low-dose quantitative spectral imaging.European radiology · 2022Article
- Spectral imaging in the pediatric chest: past, present and future.Pediatric radiology · 2022Review
- Spectral Photon-Counting Computed Tomography: A Review on Technical Principles and Clinical Applications.Journal of imaging · 2022Review
- Simultaneous dual-contrast imaging using energy-integrating detector multi-energy CT: An in vivo feasibility study.Medical physics · 2022Article
Corrections and comments
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Authors and funding
16 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesAfter endovascular aortic repair (EVAR), discrimination of endoleaks and intra-aneurysmatic calcifications within the aneurysm often requires multiphase computed tomography (CT). Spectral photon-counting CT (SPCCT) in combination with a two-contrast agent injection protocol may provide reliable detection of endoleaks with a single CT acquisition.
methodsTo evaluate the feasibility of SPCCT, the stent-lined compartment of an abdominal aortic aneurysm phantom was filled with a mixture of iodine and gadolinium mimicking enhanced blood. To represent endoleaks of different flow rates, the adjacent compartments contained either one of the contrast agents or calcium chloride to mimic intra-aneurysmatic calcifications. After data acquisition with a SPCCT prototype scanner with multi-energy bins, material decomposition was performed to generate iodine, gadolinium and calcium maps.
resultsIn a conventional CT slice, Hounsfield units (HU) of the compartments were similar ranging from 147 to 168 HU. Material-specific maps differentiate the distributions within the compartments filled with iodine, gadolinium or calcium.
conclusionSPCCT may replace multiphase CT to detect endoleaks without sacrificing diagnostic accuracy. It is a unique feature of our method to capture endoleak dynamics and allow reliable distinction from intra-aneurysmatic calcifications in a single scan, thereby enabling a significant reduction of radiation exposure. KEY POINTS: • SPCCT might enable advanced endoleak detection. • Material maps derived from SPCCT can differentiate iodine, gadolinium and calcium. • SPCCT may potentially reduce radiation burden for EVAR patients under post-interventional surveillance.
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