Evidence map›Paper›PMID 29460068›Full record

ArticleWorld journal of microbiology & biotechnology2018

Decanethiol functionalized silver nanoparticles are new powerful leishmanicidals in vitro.

A P Isaac-Márquez, P Talamás-Rohana, N Galindo-Sevilla, S E Gaitan-Puch, N A Díaz-Díaz, G A Hernández-Ballina, C M Lezama-Dávila

Abstract read
PubMed Publisher
In one paragraph

Article in World journal of microbiology & biotechnology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. In vitro leishmanicidal activity of two cholesterol derivatives.World journal of microbiology & biotechnology · 2022
    Article
  3. Article
  4. Biogenic Silver Nanoparticles Can ControlFrontiers in microbiology · 2020
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

A P Isaac-MárquezCentro de Investigaciones Biomédicas, Universidad Autónoma de Campeche, Av. Patricio Trueba de Regil s/n, Col. Lindavista, C.P. 24090, San Francisco de Campeche, Camp, Mexico. anpisaac@hotmail.com.ORCID http://orcid.org/0000-0002-7940-8118
P Talamás-RohanaDepartamento de Infectómica y Patogénesis Molecular, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional, Av. Instituto Politécnico Nacional 2508, Col. San Pedro Zacatenco, Delegación Gustavo A. Madero, C.P. 07360, Ciudad de México, Mexico.
N Galindo-SevillaDepartamento de Infectología e Inmunología, Instituto Nacional de Perinatología, Montes Urales 800, Colonia Lomas de Virreyes, C.P. 11000, Ciudad de México, Mexico.
S E Gaitan-PuchCentro de Investigaciones Biomédicas, Universidad Autónoma de Campeche, Av. Patricio Trueba de Regil s/n, Col. Lindavista, C.P. 24090, San Francisco de Campeche, Camp, Mexico.
N A Díaz-DíazCentro de Investigaciones Biomédicas, Universidad Autónoma de Campeche, Av. Patricio Trueba de Regil s/n, Col. Lindavista, C.P. 24090, San Francisco de Campeche, Camp, Mexico.
G A Hernández-BallinaCentro de Investigaciones Biomédicas, Universidad Autónoma de Campeche, Av. Patricio Trueba de Regil s/n, Col. Lindavista, C.P. 24090, San Francisco de Campeche, Camp, Mexico.
C M Lezama-DávilaCentro de Investigaciones Biomédicas, Universidad Autónoma de Campeche, Av. Patricio Trueba de Regil s/n, Col. Lindavista, C.P. 24090, San Francisco de Campeche, Camp, Mexico. lezama-davila@hotmail.com.ORCID http://orcid.org/0000-0001-5306-5287
Autonomous University of Campeche · MXInstituto Nacional de Perinatología · MXInstituto Politécnico Nacional · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We evaluated, for the first time, the leishmanicidal potential of decanethiol functionalized silver nanoparticles (AgNps-SCH) on promastigotes and amastigotes of different strains and species of Leishmania: L. mexicana and L. major isolated from different patients suffering from localized cutaneous leishmaniasis (CL) and L. mexicana isolated from a patient suffering from diffuse cutaneous leishmaniasis (DCL). We recorded the kinetics of promastigote growth by daily parasite counting for 5 days, promastigote mobility, parasite reproduction by CFSE staining's protocol and promastigote killing using the propidium iodide assay. We also recorded IC

Indexed as

AnimalsAntimony Sodium GluconateAntiprotozoal AgentsCell ProliferationHumansInhibitory Concentration 50KineticsLeishmaniaLeishmaniasis, CutaneousMacrophagesMetal NanoparticlesMiceMice, Inbred BALB CSilverAntimony Sodium GluconateAntiprotozoal AgentsSilverDecanethiol functionalized silver nanoparticlesLeishmaniasisLeishmanicidal activityL. majorL. mexicanaSilver nanoparticles

Identifiers

PMID29460068
OpenAlexW2792726354

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.