Evidence map›Paper›PMID 29459874›Full record

ReviewFrontiers in plant science2018

Traversing the Links between Heavy Metal Stress and Plant Signaling.

Siddhi K Jalmi, Prakash K Bhagat, Deepanjali Verma, Stanzin Noryang, Sumaira Tayyeba, Kirti Singh, Deepika Sharma, Alok K Sinha

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in plant science, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 90 papers.

0numbers the graph read from it
0cells of the map it votes in
90citing papers in PubMed
54.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

90 citing papers in PubMed, 335 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Plants (Basel, Switzerland) · 2025
    Article
  10. Article
  11. Role of Serotonin in Cadmium Mitigation in Plants.Plants (Basel, Switzerland) · 2025
    Review
  12. Article
  13. Article
  14. Article
  15. CaBMC plant biology · 2025
    Article
  16. Co-expression ofFrontiers in plant science · 2025
    Article
  17. Article
  18. Review
  19. Article
  20. Review

30 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Siddhi K JalmiPlant Signaling, National Institute of Plant Genome Research, New Delhi, India.
Prakash K BhagatPlant Signaling, National Institute of Plant Genome Research, New Delhi, India.
Deepanjali VermaPlant Signaling, National Institute of Plant Genome Research, New Delhi, India.
Stanzin NoryangPlant Signaling, National Institute of Plant Genome Research, New Delhi, India.
Sumaira TayyebaPlant Signaling, National Institute of Plant Genome Research, New Delhi, India.
Kirti SinghPlant Signaling, National Institute of Plant Genome Research, New Delhi, India.
Deepika SharmaPlant Signaling, National Institute of Plant Genome Research, New Delhi, India.
Alok K SinhaPlant Signaling, National Institute of Plant Genome Research, New Delhi, India.
National Institute of Plant Genome Research · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Plants confront multifarious environmental stresses widely divided into abiotic and biotic stresses, of which heavy metal stress represents one of the most damaging abiotic stresses. Heavy metals cause toxicity by targeting crucial molecules and vital processes in the plant cell. One of the approaches by which heavy metals act in plants is by over production of reactive oxygen species (ROS) either directly or indirectly. Plants act against such overdose of metal in the environment by boosting the defense responses like metal chelation, sequestration into vacuole, regulation of metal intake by transporters, and intensification of antioxidative mechanisms. This response shown by plants is the result of intricate signaling networks functioning in the cell in order to transmit the extracellular stimuli into an intracellular response. The crucial signaling components involved are calcium signaling, hormone signaling, and mitogen activated protein kinase (MAPK) signaling that are discussed in this review. Apart from signaling components other regulators like microRNAs and transcription factors also have a major contribution in regulating heavy metal stress. This review demonstrates the key role of MAPKs in synchronously controlling the other signaling components and regulators in metal stress. Further, attempts have been made to focus on metal transporters and chelators that are regulated by MAPK signaling.

Indexed as

calcium signalingchelatorsheavy metalshormonesMAPKsmetallothioneinsmetal transportersmicroRNAs

Identifiers

PMID29459874
PMCPMC5807407
OpenAlexW2786833399

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.