Evidence map›Paper›PMID 29459824›Full record

ArticleFrontiers in behavioral neuroscience2018

Bianca Pfaffenseller, Flavio Kapczinski, Amelia L Gallitano, Fábio Klamt

Open access · goldAbstract read
In one paragraph

Article in Frontiers in behavioral neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Review
  7. Intracellular Signaling Cascades in Bipolar Disorder.Current topics in behavioral neurosciences · 2021
    Review
  8. Article
  9. Article
  10. Article
  11. Deciphering GRINA/Lifeguard1: Nuclear Location, CaInternational journal of molecular sciences · 2019
    Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 3 countries.

Bianca PfaffensellerLaboratory of Molecular Psychiatry, Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.
Flavio KapczinskiDepartment of Psychiatry and Behavioral Neurosciences, McMaster University, Hamilton, ON, Canada.
Amelia L GallitanoDepartment of Basic Medical Sciences, College of Medicine, University of Arizona, Phoenix, AZ, United States.
Fábio KlamtLaboratory of Cellular Biochemistry, Department of Biochemistry, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.
Hospital de Clínicas de Porto Alegre · BRMcMaster University · CAUniversidade Federal do Rio Grande do Sul · BRUniversity of Arizona · US

Funding

Mechanism of 5HT2AR regulation by Egr3R01MH097803 · NIMH · UNIVERSITY OF ARIZONA · PI GALLITANO, AMELIA · 2012 to 2023
$3.5M
NIMH NIH HHS R01 MH097803
6 · The paper itself

Abstract

Bipolar disorder (BD) is a severe psychiatric illness with a consistent genetic influence, involving complex interactions between numerous genes and environmental factors. Immediate early genes (IEGs) are activated in the brain in response to environmental stimuli, such as stress. The potential to translate environmental stimuli into long-term changes in brain has led to increased interest in a potential role for these genes influencing risk for psychiatric disorders. Our recent finding using network-based approach has shown that the regulatory unit of early growth response gene 3 (

Indexed as

bipolar disorderbrain-derived neurotrophic factor (BDNF)early growth response gene 3 (EGR3)immediate early genesneuroplasticityregulatory network

Identifiers

PMID29459824
PMCPMC5807664
OpenAlexW2789493354

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.