Evidence map›Paper›PMID 29459773›Full record

ArticleCell death & disease2018

Erythrocyte glutathione transferase in kidney transplantation: a probe for kidney detoxification efficiency.

Alessio Bocedi, Annalisa Noce, Valentina Rovella, Giulia Marrone, Giada Cattani, Massimo Iappelli, Paolo De Paolis, Giuseppe Iaria, Daniele Sforza, Mariacarla Gallù and 3 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cell death & disease, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 33 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Alessio BocediDepartment of Chemical Sciences and Technologies, University of Rome, Tor Vergata, Via della Ricerca Scientifica, 00133, Rome, Italy.
Annalisa NoceDepartment of Systems Medicine, Hypertension and Nephrology Unit, University of Rome, Tor Vergata, Viale Oxford 81, 00133, Rome, Italy.
Valentina RovellaDepartment of Systems Medicine, Hypertension and Nephrology Unit, University of Rome, Tor Vergata, Viale Oxford 81, 00133, Rome, Italy.
Giulia MarroneDepartment of Systems Medicine, Hypertension and Nephrology Unit, University of Rome, Tor Vergata, Viale Oxford 81, 00133, Rome, Italy.
Giada CattaniDepartment of Chemical Sciences and Technologies, University of Rome, Tor Vergata, Via della Ricerca Scientifica, 00133, Rome, Italy.
Massimo IappelliNephrology and Transplant Unit, A.O.S. Camillo-Forlanini, Circonvallazione Gianicolense 87, 00152, Rome, Italy.
Paolo De PaolisNephrology and Transplant Unit, A.O.S. Camillo-Forlanini, Circonvallazione Gianicolense 87, 00152, Rome, Italy.
Giuseppe IariaLiver and kidney Transplant Centre, University of Rome, Tor Vergata, Viale Oxford 81, 00133, Rome, Italy.
Daniele SforzaLiver and kidney Transplant Centre, University of Rome, Tor Vergata, Viale Oxford 81, 00133, Rome, Italy.
Mariacarla GallùDepartment of Systems Medicine, Hypertension and Nephrology Unit, University of Rome, Tor Vergata, Viale Oxford 81, 00133, Rome, Italy.
Giuseppe TisoneLiver and kidney Transplant Centre, University of Rome, Tor Vergata, Viale Oxford 81, 00133, Rome, Italy.
Nicola Di DanieleDepartment of Systems Medicine, Hypertension and Nephrology Unit, University of Rome, Tor Vergata, Viale Oxford 81, 00133, Rome, Italy.
Giorgio RicciDepartment of Chemical Sciences and Technologies, University of Rome, Tor Vergata, Via della Ricerca Scientifica, 00133, Rome, Italy. riccig@uniroma2.it.
University of Rome Tor Vergata · ITAzienda Ospedaliera San Camillo-Forlanini · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Erythrocyte glutathione transferase (e-GST) is overexpressed in case of increased blood toxicity and its level correlates with the kidney disease progression. Thus, it represents a probe of kidney efficiency against circulating toxins. We measured the activity of e-GST in patients with transplant kidney from living and cadaver donors, correlated its level to biochemical parameters of kidney function, and measured the level of oxidized albumin as a probe of oxidative stress using a new simple procedure. Interestingly, the activity of e-GST in transplant patients from cadaver donors (N = 153) is very high (11.7 U/g

Indexed as

AdultAgedBiomarkersCadaverErythrocytesFemaleGlutathione TransferaseHumansKidneyKidney Failure, ChronicKidney TransplantationMaleMiddle AgedOxidative StressBiomarkersGlutathione Transferase

Identifiers

PMID29459773
PMCPMC5833821
OpenAlexW2791370038

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.