Evidence map›Paper›PMID 29459735›Full record

ArticleScientific reports2018

Structural heterogeneity of the rat pulmonary vein myocardium: consequences on intracellular calcium dynamics and arrhythmogenic potential.

C Pasqualin, A Yu, C O Malécot, F Gannier, C Cognard, D Godin-Ribuot, J Morand, P Bredeloux, V Maupoil

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Regional Differences in CaInternational journal of molecular sciences · 2023
    Article
  6. Preferential Expression of CaBiomolecules · 2022
    Article
  7. Article
  8. Review
  9. Article
  10. Aqueous Fraction fromNutrients · 2020
    Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

C PasqualinCNRS ERL 7368, Signalisation et Transports Ioniques Membranaires, Equipe Transferts Ioniques et Rythmicité Cardiaque, Groupe Physiologie des Cellules Cardiaques et Vasculaires, Tours, France. come.pasqualin@univ-tours.fr.ORCID 0000-0001-8625-1617
A YuCNRS ERL 7368, Signalisation et Transports Ioniques Membranaires, Equipe Transferts Ioniques et Rythmicité Cardiaque, Groupe Physiologie des Cellules Cardiaques et Vasculaires, Tours, France.
C O MalécotCNRS ERL 7368, Signalisation et Transports Ioniques Membranaires, Equipe Transferts Ioniques et Rythmicité Cardiaque, Groupe Physiologie des Cellules Cardiaques et Vasculaires, Tours, France.
F GannierCNRS ERL 7368, Signalisation et Transports Ioniques Membranaires, Equipe Transferts Ioniques et Rythmicité Cardiaque, Groupe Physiologie des Cellules Cardiaques et Vasculaires, Tours, France.
C CognardCNRS ERL 7368, Signalisation et Transports Ioniques Membranaires, Equipe Transferts Ioniques et Rythmicité Cardiaque, Poitiers, France.
D Godin-RibuotLaboratoire Hypoxie PhysioPathologie, INSERM U1042, Grenoble, France.
J MorandLaboratoire Hypoxie PhysioPathologie, INSERM U1042, Grenoble, France.
P BredelouxCNRS ERL 7368, Signalisation et Transports Ioniques Membranaires, Equipe Transferts Ioniques et Rythmicité Cardiaque, Groupe Physiologie des Cellules Cardiaques et Vasculaires, Tours, France.
V MaupoilCNRS ERL 7368, Signalisation et Transports Ioniques Membranaires, Equipe Transferts Ioniques et Rythmicité Cardiaque, Groupe Physiologie des Cellules Cardiaques et Vasculaires, Tours, France.
Centre National de la Recherche Scientifique · FRInserm · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mechanisms underlying ectopic activity in the pulmonary vein (PV) which triggers paroxysmal atrial fibrillation are unknown. Although several studies have suggested that calcium signalling might be involved in these arrhythmias, little is known about calcium cycling in PV cardiomyocytes (CM). We found that individual PV CM showed a wide range of transverse tubular incidence and organization, going from their virtual absence, as described in atrial CM, to well transversally organised tubular systems, like in ventricular CM. These different types of CM were found in groups scattered throughout the tissue. The variability of the tubular system was associated with cell to cell heterogeneity of calcium channel (Ca

Indexed as

Calcium SignalingAnimalsCalciumCalcium Channels, L-TypeHeart AtriaMyocytes, CardiacPulmonary VeinsRatsCalciumCalcium Channels, L-TypeL-type calcium channel alpha(1C)

Identifiers

PMID29459735
PMCPMC5818479
OpenAlexW2807613527

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.