Evidence map›Paper›PMID 29459730›Full record

ArticleNature communications2018

A single NaK channel conformation is not enough for non-selective ion conduction.

Chaowei Shi, Yao He, Kitty Hendriks, Bert L de Groot, Xiaoying Cai, Changlin Tian, Adam Lange, Han Sun

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
4.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 75 citations in OpenAlex.

  1. Review
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  6. High-Throughput MicroED for Probing Ion Channel Dynamics.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  7. Article
  8. Constitutive sodium permeability in aProceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  9. Article
  10. Detecting Bound Ions in Ion Channels by Solid-State NMR Experiments onMethods in molecular biology (Clifton, N.J.) · 2024
    Article
  11. Article
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  13. Mechanism of Calcium Permeation in a Glutamate Receptor Ion Channel.Journal of chemical information and modeling · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Chaowei ShiDepartment of Molecular Biophysics, Leibniz-Forschungsinstitut für Molekulare Pharmakologie, 13125, Berlin, Germany.
Yao HeHefei National Laboratory for Physical Sciences at the Microscale, School of Life Sciences, University of Science and Technology of China, 230027, Hefei, P. R. China.
Kitty HendriksDepartment of Molecular Biophysics, Leibniz-Forschungsinstitut für Molekulare Pharmakologie, 13125, Berlin, Germany.
Bert L de GrootBiomolecular Dynamics Group, Max Planck Institute for Biophysical Chemistry, 37077, Göttingen, Germany.
Xiaoying CaiHefei National Laboratory for Physical Sciences at the Microscale, School of Life Sciences, University of Science and Technology of China, 230027, Hefei, P. R. China.
Changlin TianHefei National Laboratory for Physical Sciences at the Microscale, School of Life Sciences, University of Science and Technology of China, 230027, Hefei, P. R. China. cltian@ustc.edu.cn.
Adam LangeDepartment of Molecular Biophysics, Leibniz-Forschungsinstitut für Molekulare Pharmakologie, 13125, Berlin, Germany. alange@fmp-berlin.de.
Han SunSection Structural Biology, Leibniz-Forschungsinstitut für Molekulare Pharmakologie, 13125, Berlin, Germany. hsun@fmp-berlin.de.
Leibniz-Forschungsinstitut für Molekulare Pharmakologie · DEUniversity of Science and Technology of China · CNHefei National Center for Physical Sciences at Nanoscale · CNHumboldt-Universität zu Berlin · DEMax Planck Institute for Biophysical Chemistry · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

NaK and other non-selective channels are able to conduct both sodium (Na

Indexed as

Bacterial ProteinsBinding SitesCrystallography, X-RayIon Channel GatingMembrane LipidsMolecular Dynamics SimulationNuclear Magnetic Resonance, BiomolecularPotassiumPotassium ChannelsProtein ConformationSodiumBacterial ProteinsMembrane LipidsPotassiumPotassium ChannelsSodium

Identifiers

PMID29459730
PMCPMC5818664
OpenAlexW2806096965

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.