Evidence map›Paper›PMID 29459641›Full record

ArticleScientific reports2018

Therapeutic effects of diclofenac, pregabalin, and duloxetine on disuse-induced chronic musculoskeletal pain in rats.

Yusuke Ohmichi, Mika Ohmichi, Nobuhito Murai, Masaya Yasui, Nobuaki Takeshita, Hidehiro Oshibuchi, Munekazu Naito, Takashi Nakano, Jun Sato

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Yusuke OhmichiDepartment of Anatomy, Aichi Medical University, 1-1 Yazakokarimta, Nagakute, Aichi, 480-1195, Japan. ohmichi@aichi-med-u.ac.jp.
Mika OhmichiDepartment of Anatomy, Aichi Medical University, 1-1 Yazakokarimta, Nagakute, Aichi, 480-1195, Japan.
Nobuhito MuraiPharmacology Research Laboratories, Drug Discovery Research, Astellas Pharma Inc., 21, Miyukigaoka, Tsukuba-shi, Ibaraki, 305-8585, Japan.
Masaya YasuiDepartment of Anatomy, Aichi Medical University, 1-1 Yazakokarimta, Nagakute, Aichi, 480-1195, Japan.
Nobuaki TakeshitaPharmacology Research Laboratories, Drug Discovery Research, Astellas Pharma Inc., 21, Miyukigaoka, Tsukuba-shi, Ibaraki, 305-8585, Japan.
Hidehiro OshibuchiDepartment of Psychiatry, Tokyo Women's Medical University, Kawada-cho 8-1, Shinjuku-ku, Tokyo, 162-8666, Japan.
Munekazu NaitoDepartment of Anatomy, Aichi Medical University, 1-1 Yazakokarimta, Nagakute, Aichi, 480-1195, Japan.
Takashi NakanoDepartment of Anatomy, Aichi Medical University, 1-1 Yazakokarimta, Nagakute, Aichi, 480-1195, Japan.
Jun SatoResearch Center for Next-Generation Drug Development, Research Institute of Environmental Medicine, Nagoya University, Nagoya, 464-8601, Japan.
Aichi Medical University · JPAstellas Pharma (Japan) · JPNagoya University · JPTokyo Women's Medical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to clarify the mechanism of disuse-induced muscle hyperalgesia through the evaluation of the pharmacological behaviour of muscle hyperalgesia profiles in chronic post-cast pain (CPCP) rats with acute and chronic-phase mirror-image muscle hyperalgesia treated with diclofenac (NSAID), pregabalin (an inhibitor of Ca

Indexed as

AnimalsChronic PainDiclofenacDisease Models, AnimalDuloxetine HydrochlorideHumansMuscle, SkeletalMuscular Disorders, AtrophicMusculoskeletal PainPain MeasurementPain ThresholdPregabalinRatsRats, Sprague-DawleyDiclofenacDuloxetine HydrochloridePregabalin

Identifiers

PMID29459641
PMCPMC5818528
OpenAlexW2806053768

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.