Evidence map›Paper›PMID 29459403›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2018

The Alternative NF-κB Pathway in Regulatory T Cell Homeostasis and Suppressive Function.

Yenkel Grinberg-Bleyer, Rachel Caron, John J Seeley, Nilushi S De Silva, Christian W Schindler, Matthew S Hayden, Ulf Klein, Sankar Ghosh

Open access · bronzeAbstract read
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers.

0numbers the graph read from it
0cells of the map it votes in
61citing papers in PubMed
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

61 citing papers in PubMed, 91 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Understanding the role of TNFR2 signaling in the tumor microenvironment of breast cancer.Journal of experimental & clinical cancer research : CR · 2024
    Review
  9. Advancing Animal Models of Human Type 1 Diabetes.Cold Spring Harbor perspectives in medicine · 2024
    Review
  10. Article
  11. Article
  12. MALT1 substrate cleavage: what is it good for?Frontiers in immunology · 2024
    Review
  13. Article
  14. Article
  15. Review
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article

1 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Yenkel Grinberg-BleyerDepartment of Microbiology and Immunology, College of Physicians and Surgeons, Columbia University, New York, NY 10032.ORCID 0000-0002-3515-8305
Rachel CaronDepartment of Microbiology and Immunology, College of Physicians and Surgeons, Columbia University, New York, NY 10032.ORCID 0000-0003-1421-4256
John J SeeleyDepartment of Microbiology and Immunology, College of Physicians and Surgeons, Columbia University, New York, NY 10032.
Nilushi S De SilvaDepartment of Microbiology and Immunology, College of Physicians and Surgeons, Columbia University, New York, NY 10032.
Christian W SchindlerDepartment of Microbiology and Immunology, College of Physicians and Surgeons, Columbia University, New York, NY 10032.
Matthew S HaydenDepartment of Microbiology and Immunology, College of Physicians and Surgeons, Columbia University, New York, NY 10032.
Ulf KleinDepartment of Microbiology and Immunology, College of Physicians and Surgeons, Columbia University, New York, NY 10032.ORCID 0000-0002-4789-967X
Sankar GhoshDepartment of Microbiology and Immunology, College of Physicians and Surgeons, Columbia University, New York, NY 10032; sg2715@columbia.edu.
Columbia University · US

Funding

Understanding the role of NF-kB in T-regulatory cell functionR01AI068977 · NIAID · YALE UNIVERSITY · PI GHOSH, SANKAR · 2006 to 2017
$3.9M
Regulation of NF-kB and IkB ProteinsR37AI033443 · NIAID · YALE UNIVERSITY · PI GHOSH, SANKAR · 2001 to 2010
$3.4M
NIAID NIH HHS R01 AI068977NIAID NIH HHS R37 AI033443
6 · The paper itself

Abstract

CD4

Indexed as

AnimalsAutoimmunityCell DifferentiationCells, CulturedEndonucleasesImmune ToleranceMiceMice, Inbred C57BLMice, KnockoutNF-kappa B p52 SubunitNuclear ProteinsProto-Oncogene Proteins c-relT-Lymphocytes, RegulatoryTranscription Factor RelATranscription Factor RelBEndonucleasesNF-kappa B p52 SubunitNfkb2 protein, mouseNuclear ProteinsProto-Oncogene Proteins c-relRela protein, mouseRelb protein, mouseSnd1 protein, mouseTranscription Factor RelATranscription Factor RelB

Identifiers

PMID29459403
PMCPMC5860980
OpenAlexW2787919138

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.