Evidence map›Paper›PMID 29459377›Full record

ArticleJournal of epidemiology and community health2018

Gender differences in the use of anti-infective medications before and after widowhood: a register-based study.

Adriana Santacroce, Jonas W Wastesson, Andreas Höhn, Kaare Christensen, Anna Oksuzyan

Abstract read
In one paragraph

Article in Journal of epidemiology and community health, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Adriana SantacroceDipartimento di Scienze Statistiche, Sapienza Università di Roma, Rome, Italy.
Jonas W WastessonAging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden.
Andreas HöhnDepartment of Epidemiology, Biostatistics and Biodemography, University of Southern Denmark, Odense C, Denmark.
Kaare ChristensenDepartment of Epidemiology, Biostatistics and Biodemography, University of Southern Denmark, Odense C, Denmark.
Anna OksuzyanMax Planck Institute for Demographic Research, Rostock, Germany.

Funding

THE RANGE OF MALE-FEMALE MORTALITY DIFFERENCESP01AG031719 · NIA · DUKE UNIVERSITY · PI CHRISTENSEN, KAARE · 2009 to 2020
$10.2M
NIA NIH HHS P01 AG031719
6 · The paper itself

Abstract

backgroundRecent findings suggest that bereavement due to spousal loss is associated with a decline in general immune functions, and thus to increased susceptibility to infections among widowed individuals. The present study aims to investigate whether spousal loss weakens immune defences more among men than among women using a 5% random sample of the total Danish population, and anti-infective medication use as a proxy for immune response.

methodsWe followed 6076 Danish individuals (67% women) aged ≥50 from 5 years before and up to 5 years after widowhood to examine changes in prescriptions of anti-infectives for systemic use.

resultsWomen used more anti-infective drugs both before and after spousal loss (women: OR= 1.31; 95% CI 1.21 to 1.42). The age-related changes in the use of anti-infective medications in the period before widowhood were similar to that in the period after widowhood among both men and women. Also, age-related changes in the use of anti-infective medications were similar in both genders.

conclusionsThe present study shows that individuals are more likely to use anti-infective medication after being widowed than before being widowed, but this change is likely to be related to increasing age and it is similar in both genders.

Indexed as

BereavementHealth StatusAgedAnti-Infective AgentsDenmarkFemaleHumansInfectionsMaleMarital StatusMiddle AgedRegistriesSex FactorsWidowhoodAnti-Infective Agentsage and cohort effectsgender differencesimmune responsewidowhood

Identifiers

PMID29459377
PMCPMC5948149

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.